Whole grain consumption and human health: an umbrella review of observational studies
Tieri M, Ghelfi F, Vitale M, Vetrani C, Marventano S, Lafranconi A, Godos J, Titta L, Gambera A, Alonzo E, Sciacca S, Riccardi G, Buscemi S, Del Rio D, Ray S, Galvano F, Beck E, Grosso G
International journal of food sciences and nutrition · 85 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-01-21 · Int J Food Sci Nutr · vol. 71 · issue 6 · pp. 668–677
- Publisher
- Taylor & Francis
- Cited
- 140 citations · more than 99% of similar papers · 10.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 73 works
- Access
- Open access (repository copy) · OTHER-OA
- Research areas
- Food composition and properties · Nutritional Studies and Diet · Nutrition and Health in Aging
- Keywords
- Observational study, Whole grains, Medicine, Colorectal cancer, Environmental health, Consumption (sociology), Prostate cancer, Type 2 diabetes, Diabetes mellitus, Cancer, Internal medicine, Endocrinology, Food science, Biology
- MeSH
- humans, colorectal neoplasms, colonic neoplasms, prostatic neoplasms, cardiovascular diseases, diabetes mellitus, type 2, diet, health status, eating, dietary fiber, female, male, observational studies as topic, whole grains
18 authors
From IT, NL, GB, AU
- Maria TieriEuropean Institute of Oncology
- Francesca GhelfiFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Marilena VitaleFederico II University Hospital
- Claudia VetraniFederico II University Hospital
- Stefano MarventanoAzienda Unità Sanitaria Locale Rimini
- Alessandra LafranconiMaastricht University; Care and Public Health Research Institute; University of Milano-Bicocca
Abstract
Whole grains have been associated with a number of health benefits. We systematically reviewed existing meta-analyses of observational studies and evaluated the level of evidence for their putative effects based on pre-selected criteria. Of the 23 included studies, we found convincing evidence of an inverse association between whole grain consumption and risk of type-2 diabetes and colorectal cancer; possible evidence of decreased risk of colon cancer and cardiovascular mortality with increased whole grain intake, as well as increased risk of prostate cancer. Limited or insufficient evidence was available for all other outcomes investigated. Overall findings are encouraging for a positive effect of whole grain consumption on certain diseases, especially highly prevalent metabolic diseases, however, uncertainty of some negative associations deserves further attention.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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