Egg Consumption and Coronary Artery Disease: A Nice Knockdown Argument
Takagi H, Hari Y, Nakashima K, Kuno T, Ando T
Angiology · 5 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-01-31 · Angiology · vol. 71 · issue 7 · pp. 589–601
- Publisher
- SAGE Publishing
- Cited
- 8 citations · more than 82% of similar papers · 1.4× the field average
- References
- 29 works
- Access
- Paywalled
- Research areas
- Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Sodium Intake and Health
- Keywords
- Medicine, Coronary artery disease, Argument (complex analysis), Cardiology, Gene knockdown, Internal medicine, Nice, Consumption (sociology), Disease
- MeSH
- humans, incidence, risk factors, cohort studies, prospective studies, feeding behavior, eggs, adult, female, male, coronary artery disease
5 authors
From JP, US
- Hisato TakagiShizuoka Medical Center; Kitasato University
- Yosuke HariShizuoka Medical Center; Kitasato University
- Kouki NakashimaShizuoka Medical Center; Kitasato University
- Toshiki KunoMount Sinai Beth Israel
- Tomo AndoNewYork–Presbyterian Hospital; Columbia University Irving Medical Center; New York Hospital Queens
Abstract
To identify prospective cohort studies enrolling adults and investigating an association of egg consumption with incidence and mortality of coronary artery disease (CAD), PubMed and Web of Science were searched through June 2019. Adjusted hazard ratios (HRs) of CAD incidence/mortality for more versus the least frequent egg consumption were extracted from each study. Study-specific estimates were pooled in the random-effects model. Sixteen eligible studies with a total of 1 285 505 participants were identified and included in the present meta-analysis. The primary meta-analysis pooling all HRs for the most versus least frequent egg consumption demonstrated that egg consumption was associated with significantly low CAD incidence/mortality (pooled HR: 0.93; 95% confidence interval: 0.89-0.98; I2 = 9%). In the secondary meta-analyses (separately combining HRs for the third vs first tertile, the fourth vs first quartile, the third vs first quartile, the fifth vs first quintile, the fourth vs first quintile, and the third vs first quintile egg consumption), the fifth (vs first) quintile egg consumption was only associated with significantly low CAD incidence/mortality. In conclusion, egg consumption is independently associated with low incidence/mortality of CAD, which may be derived from the comparisons of the fifth versus first quintile egg consumption.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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