Funded in part by Novo Nordisk, Novo Nordisk Fonden
A Delayed Morning and Earlier Evening Time-Restricted Feeding Protocol for Improving Glycemic Control and Dietary Adherence in Men with Overweight/Obesity: A Randomized Controlled Trial
Parr EB, Devlin BL, Radford BE, Hawley JA
Nutrients · 131 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Industry funded
- University or hospital
- Australian Catholic University
- Company
- Novo Nordisk
- Company
- Novo Nordisk Fonden
- University or hospital
- Baker Heart and Diabetes Institute
- Grants
- Australian Catholic University (ACURF2016000353); Novo Nordisk Fonden (NNF14OC0011493)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2020-02-17 · Nutrients · vol. 12 · issue 2 · p. 505
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 169 citations · more than 99% of similar papers · 11.7× the field average
- Impact
- Top 10% most cited in its field
- References
- 43 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Circadian rhythm and melatonin · Diet and metabolism studies
- Keywords
- Postprandial, Morning, Evening, Overweight, Glycemic, Medicine, Crossover study, Endocrinology, Internal medicine, Obesity, Randomized controlled trial, Insulin, Appetite, Type 2 diabetes, Area under the curve, Diabetes mellitus, Placebo
- MeSH
- humans, diabetes mellitus, type 2, obesity, insulin, blood glucose, treatment outcome, fasting, cross-over studies, patient compliance, energy intake, time factors, adult, male, overweight, incretins, meals, sedentary behavior
4 authors
From AU
- Evelyn B. Parr · correspondingAustralian Catholic University
- Brooke L. DevlinLa Trobe University; Australian Catholic University
- Bridget E. RadfordAustralian Catholic University
- John A. HawleyAustralian Catholic University
Abstract
We determined the effects of time-restricted feeding (TRF; 8 h/d) versus extended feeding (EXF; 15 h/d) on 24-h and postprandial metabolism and subjective opinions of TRF in men with overweight/obesity. In a randomized crossover design, 11 sedentary males (age 38 ± 5 y; BMI: 32.2 ± 2.0 kg/m2) completed two isoenergetic diet protocols for 5 days, consuming meals at 1000, 1300 and 1700 h (TRF) or 0700, 1400 and 2100 h (EXF). On Day 5, participants remained in the laboratory for 24 h, and blood samples were collected at hourly (0700-2300 h) then 2-hourly (2300-0700 h) intervals for concentrations of glucose, insulin and appetite/incretin hormones. Structured qualitative interviews were conducted following completion of both dietary conditions and investigated thematically. Total 24-h area under the curve (AUCtotal) [glucose] tended to be lower for TRF versus EXF (-5.5 ± 9.0 mmol/L/h, P = 0.09). Nocturnal glucose AUC was lower in TRF (-4.2 ± 5.8 mmol/L/h, P = 0.04), with no difference in waking glucose AUC or AUCtotal for [insulin]. Attitudes towards TRF were positive with improved feelings of well-being. Barriers to TRF were work schedules, family commitments and social events. Compared to extended feeding, short-term TRF improved nocturnal glycemic control and was positively perceived in men with overweight/obesity.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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