Red and Processed Meat, Poultry, Fish, and Egg Intakes and Cause-Specific and All-Cause Mortality among Men with Nonmetastatic Prostate Cancer in a U.S. Cohort
Wang Y, Jacobs EJ, Shah RA, Stevens VL, Gansler T, McCullough ML
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 14 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Nonprofit
- American Cancer Society
Based on 1 listed funder(s).
Publication
- Published
- 2020-03-04 · Cancer Epidemiol Biomarkers Prev · vol. 29 · issue 5 · pp. 1029–1038
- Publisher
- American Association for Cancer Research
- Cited
- 25 citations · more than 93% of similar papers · 3.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 35 works
- Access
- Paywalled
- Research areas
- Nutritional Studies and Diet · Prostate Cancer Diagnosis and Treatment · Nutrition and Health in Aging
- Keywords
- Prostate cancer, Medicine, Red meat, Quartile, Cancer, Cohort study, Cohort, Relative risk, Confidence interval, Proportional hazards model, Lower risk, Prostate, Internal medicine, Gynecology, Pathology
- MeSH
- animals, poultry, fishes, humans, prostatic neoplasms, cardiovascular diseases, diet surveys, cause of death, risk assessment, follow-up studies, feeding behavior, nutrition policy, eggs, meat products, aged, united states, male, red meat, cancer survivors
6 authors
From US
- Ying Wang · correspondingAmerican Cancer Society
- Eric J. JacobsAmerican Cancer Society
- Roma A. ShahAmerican Cancer Society
- Victoria L. StevensAmerican Cancer Society
- Ted S. GanslerAmerican Cancer Society
- Marjorie L. McCulloughAmerican Cancer Society
Abstract
Background
Research on the relationship of meat, fish, and egg consumption and mortality among prostate cancer survivors is limited.
Methods
In the Cancer Prevention Study-II Nutrition Cohort, men diagnosed with nonmetastatic prostate cancer between baseline in 1992/1993 and 2015 were followed for mortality until 2016. Analyses of pre- and postdiagnosis intakes of red and processed meat, poultry, fish, and eggs included 9,286 and 4,882 survivors, respectively. Multivariable-adjusted RRs and 95% confidence intervals (CI) were estimated using Cox proportional hazards models.
Results
A total of 4,682 and 2,768 deaths occurred during follow-up in pre- and postdiagnosis analyses, respectively. Both pre- and postdiagnosis intakes of total red and processed meat were positively associated with all-cause mortality (quartile 4 vs. 1: RR = 1.13; 95% CI, 1.03-1.25; P trend = 0.02; RR = 1.22; 95% CI, 1.07-1.39; P trend = 0.03, respectively), and both pre- and postdiagnosis poultry intakes were inversely associated with all-cause mortality (quartile 4 vs. 1 RR = 0.90; 95% CI, 0.82-0.98; P trend = 0.04; RR = 0.84; 95% CI, 0.75-0.95; P trend = 0.01, respectively). No associations were seen for prostate cancer-specific mortality, except that higher postdiagnosis unprocessed red meat intake was associated with lower risk.
Conclusions
Higher red and processed meat, and lower poultry, intakes either before or after prostate cancer diagnosis were associated with higher risk of all-cause mortality.
Impact
Our findings provide additional evidence that prostate cancer survivors should follow the nutrition guidelines limiting red and processed meat consumption to improve overall survival. Additional research on the relationship of specific meat types and mortality is needed.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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