Whole grain intake compared with cereal fibre intake in association to CVD risk factors: a cross-sectional analysis of the National Diet and Nutrition Survey (UK)
Barrett EM, Amoutzopoulos B, Batterham MJ, Ray S, Beck EJ
Public health nutrition · 22 citations
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- Australian Government
Based on 1 listed funder(s).
Publication
- Published
- 2020-03-19 · Public Health Nutr · vol. 23 · issue 8 · pp. 1392–1403
- Publisher
- Cambridge University Press
- Cited
- 25 citations · more than 82% of similar papers · 1.6× the field average
- References
- 47 works
- Access
- Free to read
- Research areas
- Food composition and properties · Nutritional Studies and Diet · Celiac Disease Research and Management
- Keywords
- Quartile, Medicine, Whole grains, Cross-sectional study, Homocysteine, Waist, Refined grains, Dietary fibre, Body mass index, Breakfast cereal, Animal science, Food science, Environmental health, Internal medicine, Biology, Confidence interval
- MeSH
- humans, cardiovascular diseases, c-reactive protein, diet, nutrition surveys, risk factors, cross-sectional studies, dietary fiber, adult, edible grain, whole grains, united kingdom, glycated hemoglobin
5 authors
From AU, GB
- Eden M. Barrett · correspondingUniversity of Wollongong; Illawarra Health and Medical Research Institute
- Birdem AmoutzopoulosMRC Elsie Widdowson Laboratory; University of Cambridge; MRC Epidemiology Unit
- Marijka Jane BatterhamUniversity of Wollongong; Illawarra Health and Medical Research Institute
- Sumantra RayMRC Elsie Widdowson Laboratory; British Dietetic Association; Cambridge University Health Partners
- Eleanor J. BeckUniversity of Wollongong; Illawarra Health and Medical Research Institute
Abstract
Objective
To investigate how intakes of whole grains and cereal fibre were associated to risk factors for CVD in UK adults.
Design
Cross-sectional analyses examined associations between whole grain and cereal fibre intakes and adiposity measurements, serum lipid concentrations, C-reactive protein, systolic blood pressure, fasting glucose, HbA1c, homocysteine and a combined CVD relative risk score.
Setting
The National Diet and Nutrition Survey (NDNS) Rolling Programme 2008-2014.
Participants
A nationally representative sample of 2689 adults.
Results
Participants in the highest quartile (Q4) of whole grain intake had lower waist-hip ratio (Q1 0·872; Q4 0·857; P = 0·04), HbA1c (Q1 5·66 %; Q4 5·47 %; P = 0·01) and homocysteine (Q1 9·95 µmol/l; Q4 8·76 µmol/l; P = 0·01) compared with participants in the lowest quartile (Q1), after adjusting for dietary and lifestyle factors, including cereal fibre intake. Whole grain intake was inversely associated with C-reactive protein using multivariate analysis (P = 0·02), but this was not significant after final adjustment for cereal fibre. Cereal fibre intake was also inversely associated with waist-hip ratio (P = 0·03) and homocysteine (P = 0·002) in multivariate analysis.
Conclusions
Similar inverse associations between whole grain and cereal fibre intakes to CVD risk factors suggest the relevance of cereal fibre in the protective effects of whole grains. However, whole grain associations often remained significant after adjusting for cereal fibre intake, suggesting additional constituents may be relevant. Intervention studies are needed to compare cereal fibre intake from non-whole grain sources to whole grain intake.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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