Longitudinal associations between ultra-processed foods and blood lipids in childhood
Leffa PS, Hoffman DJ, Rauber F, Sangalli CN, Valmórbida JL, Vitolo MR
The British journal of nutrition · 70 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Food diaries or recalls
Who paid for it
- Funding
- Independent funding
- Government
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Government
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Government
- Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul
- Government
- Ministério da Saúde
- Grants
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (88881); Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (577/200); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (14_2013); Conselho Nacional de Desenvolvimento Científico e Tecnológico (14/2013-47731/2013-8); Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (14/2013-47731/2013-8); Ministério da Saúde (577/200); Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (14/2013); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (2019‐01); Conselho Nacional de Desenvolvimento Científico e Tecnológico (14/2013); Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (PPSUS/2006/1537‐7); Conselho Nacional de Desenvolvimento Científico e Tecnológico (88881); Conselho Nacional de Desenvolvimento Científico e Tecnológico (2013-8); Fundação de Amparo à Pesquisa do Estado do Rio Grande do Sul (88881)
Based on 4 listed funder(s).
Publication
- Published
- 2020-04-06 · Br J Nutr · vol. 124 · issue 3 · pp. 341–348
- Publisher
- Cambridge University Press
- Cited
- 91 citations · more than 98% of similar papers · 8.8× the field average
- Impact
- Top 10% most cited in its field
- References
- 60 works
- Access
- Free to read
- Research areas
- Consumer Attitudes and Food Labeling · Obesity, Physical Activity, Diet · Nutritional Studies and Diet
- Keywords
- Medicine, Blood lipids, Food consumption, Cholesterol, Animal science, Internal medicine, Biology
- MeSH
- humans, lipids, diet, diet surveys, linear models, longitudinal studies, follow-up studies, energy intake, poverty, food handling, child, child, preschool, brazil, female, male, randomized controlled trials as topic
6 authors
From BR, US
- Paula dos Santos Leffa · correspondingUniversidade Federal de Ciências da Saúde de Porto Alegre
- Daniël J. HoffmanRutgers, The State University of New Jersey
- Fernanda RauberUniversidade de São Paulo
- Caroline Nicola SangalliUniversidade Federal de Ciências da Saúde de Porto Alegre
- Julia Luzzi ValmórbidaUniversidade Federal de Ciências da Saúde de Porto Alegre
- Márcia Regina VítoloUniversidade Federal de Ciências da Saúde de Porto Alegre
Abstract
Emerging evidence suggests that the consumption of ultra-processed foods (UPF) plays a role in the development of chronic diseases, but evidence of their influence in children is limited. Our objective was to study longitudinal trends of UPF intake and determine their impact on blood lipids in young children. The present study was a follow-up of a randomised field trial of children (n 308) from Porto Alegre, Brazil. Dietary intake was collected using two 24-h recalls at 3 and 6 years of age, and consumption of UPF was classified according to the NOVA system, a food classification based on the extent and purpose of industrial food processing. At age 6 years, blood tests were performed to measure lipid profile. Contribution of UPF to total energy intake increased by 10 % during the follow-up period, from 43·4 % at 3 years to 47·7 % at 6 years of age. Linear regression models showed that children in the highest tertile of UPF consumption at age 3 years had higher levels of total cholesterol (TC; β 0·22 mmol/l; 95 % CI 0·04, 0·39) and TAG at age 6 years (β 0·11 mmol/l, 95 % CI 0·01, 0·20) compared with those in the lowest tertile. A positive dose-response was observed for an absolute increment of 10 % of UPF on TC (β 0·07 mmol/l, 95 % CI 0·00, 0·14) and TAG (β 0·04 mmol/l, 95 % CI 0·01, 0·07). Based on our data, consumption of UPF increased significantly over time and was associated with higher blood lipid levels in children from a low-income community. Our findings highlight the need for effective strategies to minimise the consumption of UPF in early life.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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