Effects of Ashwagandha (Withania somnifera) on VO2max: A Systematic Review and Meta-Analysis
Pérez-Gómez J, Villafaina S, Adsuar JC, Merellano-Navarro E, Collado-Mateo D
Nutrients · 18 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-04-17 · Nutrients · vol. 12 · issue 4 · p. 1119
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 54 citations · more than 89% of similar papers · 2.6× the field average
- References
- 57 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Phytochemicals and Medicinal Plants · Cardiovascular and exercise physiology · Cardiovascular Effects of Exercise
- Keywords
- Withania somnifera, Meta-analysis, Systematic review, Randomized controlled trial, Medicine, Quality of evidence, Physical therapy, Grading (engineering), MEDLINE, VO2 max, Traditional medicine, Alternative medicine, Internal medicine, Biology, Pathology
- MeSH
- humans, withania, plant extracts, oxygen consumption, physical fitness, dietary supplements, adult, female, male, athletes
5 authors
From ES, CL
- Jorge Pérez‐GómezUniversidad de Extremadura
- Santos Villafaina · correspondingUniversidad de Extremadura
- José Carmelo AdsuarUniversidad de Extremadura
- Eugenio Merellano-NavarroUniversidad Autónoma de Chile
- Daniel Collado‐MateoUniversidad Rey Juan Carlos
Abstract
The purpose of this study was to systematically review the scientific literature about the effects of supplementation with Ashwagandha (Withania somnifera) on maximum oxygen consumption (VO2max), as well as to provide directions for clinical practice. A systematic search was conducted in three electronic databases following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Guidelines (PRISMA). The inclusion criteria were: (a) VO2max data, with means ± standard deviation before and after the supplement intervention, (b) the study was randomized controlled trial (RCT), (c) the article was written in English. The quality of evidence was evaluated according to the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach. A meta-analysis was performed to determine effect sizes. Five studies were selected in the systematic review (162 participants) and four were included in the meta-analysis (142 participants). Results showed a significant enhancement in VO2max in healthy adults and athletes (p = 0.04). The mean difference was 3.00 (95% CI from 0.18 to 5.82) with high heterogeneity. In conclusion, Ashwagandha supplementation might improve the VO2max in athlete and non-athlete people. However, further research is need to confirm this hypothesis since the number of studies is limited and the heterogeneity was high.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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