Randomized controlled trial2020Open access

The addition of β-Hydroxy β-Methylbutyrate (HMB) to creatine monohydrate supplementation does not improve anthropometric and performance maintenance across a collegiate rugby season

Mangine GT, VanDusseldorp TA, Hester GM, Julian JM, Feito Y

Journal of the International Society of Sports Nutrition · 6 citations

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
University or hospital
Kennesaw State University

Based on 1 listed funder(s) and full-text disclosure statement.

Publication

Published
2020-01-03 · J Int Soc Sports Nutr · vol. 17 · issue 1 · p. 28
Publisher
Springer Science+Business Media
Cited
10 citations · more than 57% of similar papers · 0.5× the field average
References
62 works
Access
Open access (journal) · CC-BY
Research areas
Muscle metabolism and nutrition · Sports Performance and Training · Exercise and Physiological Responses
Keywords
Medicine, Lean body mass, Repeated measures design, Bench press, Creatine Monohydrate, Creatine, Animal science, Anthropometry, Athletes, Placebo, Regimen, Physical therapy, Internal medicine, Endocrinology, Biology, Body weight
MeSH
humans, creatine, valerates, hydrocortisone, creatine kinase, cross-over studies, double-blind method, body composition, football, dietary supplements, male, athletic performance, young adult, sports nutritional physiological phenomena

5 authors

From US

  • Gerald T. Mangine · correspondingKennesaw State University
  • Trisha A. VanDusseldorpKennesaw State University
  • Garrett M. HesterKennesaw State University
  • J.M. Gutiérrez JuliánKennesaw State University
  • Yuri FeitoKennesaw State University

Abstract

Background

Muscular damage sustained while playing rugby may hinder performance across a season. β-Hydroxy β-Methylbutyrate (HMB) may help attenuate muscle damage and maintain lean mass and performance. This study sought to determine the effect of combining HMB with creatine monohydrate supplementation on measures of stress and muscle damage, body composition, strength and sprinting kinetics throughout a rugby season.

Methods

This double-blind, cross-over investigation recruited 16 male collegiate rugby players to provide resting blood samples and complete assessments of body composition, strength and sprinting performance prior to their fall season (PREFALL). After testing, the athletes were matched for fat-free mass and assigned to consume one of two supplementation regimens for 6 weeks: 5 g HMB + 5 g creatine per day (HMB-Cr: 20.9 ± 1.1 years; 177 ± 2 cm; 88.4 ± 4.9 kg) or 5 g creatine + 5 g placebo per day (Cr: 21.4 ± 2.1 years; 179 ± 2 cm; 88.3 ± 4.9 kg). After 6 weeks (POSTFALL), PREFALL testing was repeated in 13 of the original 16 athletes before a 10-wk wash-out period. Athletes who returned for the spring season (n = 8) repeated all fall-season procedures and testing prior to (PRESPRING) and following (POSTSPRING) their 6-wk spring season, except they were assigned to the opposite supplementation regimen.

Results

Linear mixed models with repeated measures revealed group x time interactions (p - 1, p = 0.003) and impulse (~ 4.5 Nm·sec, p = 0.022) were observed in Cr at PRESPRING but not at POSTSPRING. Although significant interactions were found for cortisol concentrations, vastus lateralis pennation angle, and sprinting force, post-hoc analysis only revealed differences between fall and spring seasons. No other differences were observed.

Conclusions

The combination of HMB and creatine monohydrate supplementation does not provide a greater ergogenic benefit compared to creatine monohydrate supplementation alone. Body composition, strength, and sprinting ability did not change across the season with creatine monohydrate supplementation.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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