Meta-analysis of the association between nut consumption and the risks of cancer incidence and cancer-specific mortality
Zhang D, Dai C, Zhou L, Li Y, Liu K, Deng YJ, Li N, Zheng Y, Hao Q, Yang S, Song D, Wu Y, Zhai Z, Cao S, Dai Z
Aging · 34 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2020-06-02 · Aging (Albany NY) · vol. 12 · issue 11 · pp. 10772–10794
- Publisher
- Impact Journals LLC
- Cited
- 45 citations · more than 84% of similar papers · 1.7× the field average
- References
- 58 works
- Access
- Open access (repository copy) · CC-BY
- Research areas
- Nuts composition and effects · Nutritional Studies and Diet
- Keywords
- Nut, Cancer incidence, Medicine, Meta-analysis, Incidence (geometry), Environmental health, Cancer, Consumption (sociology), Demography, Association (psychology), Oncology, Internal medicine, Mathematics, Psychology, Engineering
- MeSH
- humans, nuts, neoplasms, diet, incidence, mortality
15 authors
From CN
- Dai ZhangSecond Affiliated Hospital of Xi'an Jiaotong University; Zhejiang University
- Cong Dai
- Linghui ZhouSecond Affiliated Hospital of Xi'an Jiaotong University; Zhejiang University
- Yiche LiHebei Medical University; Fourth Hospital of Hebei Medical University
- Kang LiuFirst Affiliated Hospital of Xi'an Jiaotong University
- Yujiao DengSecond Affiliated Hospital of Xi'an Jiaotong University; Zhejiang University
Abstract
Previous studies have indicated a correlation between nut intake and cancer risk in humans. This meta-analysis aimed to determine the relationship between nut consumption and the risks of cancer incidence and mortality. The PubMed, Embase, and Web of Science databases were searched up to August 2019. Relative risks and 95% confidence intervals were calculated using random-effects and fixed-effects models. We included 38 studies on nut consumption and cancer risk and 9 studies on cancer-specific mortality. Compared with no nut intake, nut intake was associated with a lower cancer risk (Relative Risk=0.90; 95% confidence interval, 0.86-0.94). Inverse associations were observed with colorectal cancer, gastric cancer, pancreatic cancer, and lung cancer in subgroup analyses. Tree nut consumption was found to reduce cancer risk (Relative Risk=0.88; 95% confidence interval, 0.79-0.99). Dose-response curves suggested that protective benefits against cancer increased with increased nut intake (P=0.005, P-nonlinearity=0.0414). An inverse correlation with cancer-specific mortality (Odd Ratio=0.90; 95% confidence interval, 0.88-0.92) was observed. In conclusion, nut consumption is inversely associated with the risks of cancer incidence and mortality; a higher intake is significantly associated with a lower cancer risk.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.