Magnesium Supplementation Shortens Hemodialysis-Associated Prolonged QT
Umapathi KK, Lee S, Jacobson J, Jandeska S, Nguyen HH
Cureus · 2 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case report (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-07-11 · Cureus · vol. 12 · issue 7 · p. e9132
- Publisher
- Cureus, Inc.
- Cited
- 5 citations · more than 57% of similar papers · 0.3× the field average
- References
- 20 works
- Access
- Open access (free to publish) · CC-BY
- Research areas
- Magnesium in Health and Disease · Cardiac electrophysiology and arrhythmias · Potassium and Related Disorders
- Keywords
- Medicine, Hemodialysis, QT interval, Repolarization, Cardiology, Internal medicine, Anesthesia, Intensive care medicine, Electrophysiology
5 authors
From US
- Krishna Kishore Umapathi · correspondingRush University Medical Center; Children's Hospital of Los Angeles; The University of Texas Southwestern Medical Center
- Sun-Ah LeeRush University Medical Center; Children's Hospital of Los Angeles; The University of Texas Southwestern Medical Center
- Jessica L. JacobsonRush University Medical Center; Children's Hospital of Los Angeles; The University of Texas Southwestern Medical Center
- Sara JandeskaRush University Medical Center; Children's Hospital of Los Angeles; The University of Texas Southwestern Medical Center
- Hoang H. NguyenRush University Medical Center; Children's Hospital of Los Angeles; The University of Texas Southwestern Medical Center
Abstract
Hemodialysis affects myocardial depolarization and repolarization notably lengthening the QT interval. Prolonged QT, in turn, has been a reliable surrogate for higher risk of potentially lethal ventricular arrhythmias. We present an adolescent girl with end-stage kidney disease who consistently developed prolonged QT following hemodialysis sessions. Interestingly, her QT intervals were inversely correlated with her serum magnesium levels. Magnesium supplementation appeared to help reduce the QT prolongation after hemodialysis. Our case shows the potential utility of magnesium as a cardioprotective agent in hemodialysis patients. We recommend that patients undergoing hemodialysis receive frequent electrocardiograms and electrolytes monitoring for tailored electrolytes management to reduce the risk of developing potentially lethal cardiac arrhythmias.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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