A Pilot Study on the Effects of Nut Consumption on Cardiovascular Biomarkers
Adashek JJ, Redding D
Cureus · 3 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Controlled clinical trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-06-24 · Cureus · vol. 12 · issue 6 · p. e8798
- Publisher
- Cureus, Inc.
- Cited
- 5 citations · more than 64% of similar papers · 0.6× the field average
- References
- 16 works
- Access
- Open access (free to publish) · CC-BY
- Research areas
- Nuts composition and effects · Antioxidant Activity and Oxidative Stress · Ginger and Zingiberaceae research
- Keywords
- Medicine, Cholesterol, Internal medicine, Disease, Cardiology, Gastroenterology
2 authors
From US
- Jacob J. Adashek · correspondingUniversity of South Florida; Western University of Health Sciences
- David C. ReddingUniversity of South Florida; Western University of Health Sciences
Abstract
Background
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality in the United States and changes in lifestyle can minimize the likelihood of succumbing to heart disease. Anti-inflammatory agents are commonly used to reduce the chronic inflammatory state behind the pathogenesis of CVD. Multiple studies have been published correlating nut consumption with a reduction in both heart attacks and strokes. The goal of this study is to determine to what extent the consumption of almonds, hazelnuts, and walnuts have on the blood markers associated with cardiac disease and inflammation.
Methods
This was a six-week study in which subject's baseline values act as controls. Fasting blood draws occurred at week 0, week 2, and after four weeks of intervention (week 6). All participants had undesirable lipid profiles and no medications related to heart disease.
Results
Total cholesterol (TC): high-density lipoprotein (HDL-C) ratio was lowered a statistically significant amount at the six-week time point (3.89 ± 0.74) compared to both the zero-week (4.93 ± 1.16, p < 0.01) and two-week (4.63 ± 1.20, p < 0.5) timepoints. Low-density lipoprotein (LDL) measurements were lowered a statistically significant amount at the six-week time point (135.6 ± 15.0 mg/dL) compared to the zero-week (159.7 ± 12.3 mg/dL, p < 0.01). Erythrocyte sedimentation rate (ESR) was lowered a statistically significant amount at six-week time point (10.44 ± 5.05 mm/h) compared to the zero-week (14.44 ± 5.12 mm/h, p < 0.01).
Conclusions
Blood markers associated with CVD specifically and the general marker for inflammation associated with many chronic diseases can be favorably modified with the consumption of specific nuts as demonstrated by this study.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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