Effects of Ramadan Intermittent Fasting on Gut Hormones and Body Composition in Males with Obesity
Zouhal H, Bagheri R, Triki R, Saeidi A, Wong A, Hackney AC, Laher I, Suzuki K, Ben Abderrahman A
International journal of environmental research and public health · 48 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-08-03 · Int J Environ Res Public Health · vol. 17 · issue 15 · p. 5600
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 69 citations · more than 95% of similar papers · 4.1× the field average
- Impact
- Top 10% most cited in its field
- References
- 55 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Regulation of Appetite and Obesity · Diet and metabolism studies
- Keywords
- Peptide YY, Ghrelin, Leptin, Internal medicine, Cholecystokinin, Hormone, Endocrinology, Appetite, Medicine, Obesity, Intermittent fasting, Glucagon-like peptide-1, Diabetes mellitus, Neuropeptide, Type 2 diabetes, Neuropeptide Y receptor
- MeSH
- humans, obesity, gastrointestinal hormones, fasting, body composition, male, gastrointestinal microbiome
9 authors
From FR, IR, US, TN, CA, JP
- Hassane Zouhal · correspondingUniversité Rennes 2; Laboratoire Mouvement Sport Santé
- Reza BagheriUniversity of Isfahan
- Raoua TrikiInstitute of Semitic Studies; Manouba University
- Ayoub SaeidiIslamic Azad University, Damghan Branch
- Alexei WongMarymount University; Marymount Manhattan College
- Anthony C. HackneyUniversity of North Carolina at Chapel Hill; University of North Carolina System
Abstract
We studied the effects of Ramadan intermittent fasting (RIF) on gut hormones (leptin, glucagon-like peptide-1 (GLP-1), peptide YY (PYY), cholecystokinin (CCK), and ghrelin) in males with obesity. Thirty sedentary males were randomly allocated to either an experimental group (EG, n = 15) or a control group (CG, n = 15). The EG group completed their Ramadan fasting rituals (30 days), whereas the CG continued with their normal daily habits. Blood samples were collected at four time points: 24 h before the start of Ramadan (T0), on the 15th day of Ramadan (T1), the day after the end of Ramadan (T2) and 21 days after Ramadan (T3). There were significant pre-to-post improvements for leptin (p = 0.01, d = 1.52), GLP-1 (p = 0.022, d = 0.75), PYY (p = 0.031, d = 0.69) and CCK (p = 0.027, d = 0.81) in the EG, with no interaction effect for ghrelin (p = 0.74; d = 0.008). No significant changes (p > 0.05) occurred in plasma volume variations (ΔPV) after RIF in both EG (-0.03 ± 0.01%) and CG (0.06 ± 0.07%). RIF represents an effective strategy to modify appetite-regulating hormones, leading to improved body composition indices and reduced obesity.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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