The Effect of Acute Hypohydration on Indicators of Glycemic Regulation, Appetite, Metabolism and Stress: A Systematic Review and Meta-Analysis
Zaplatosch ME, Adams WM
Nutrients · 8 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- University or hospital
- University of North Carolina at Greensboro
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2020-08-20 · Nutrients · vol. 12 · issue 9 · p. 2526
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 11 citations · more than 30% of similar papers · 0.1× the field average
- References
- 129 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Thermoregulation and physiological responses · Dietary Effects on Health · Exercise and Physiological Responses
- Keywords
- Ghrelin, Appetite, Internal medicine, Medicine, Peptide YY, Endocrinology, Anabolism, Leptin, Glycemic, Glucagon, Hormone, Sarcopenia, Insulin, Obesity
- MeSH
- humans, dehydration, testosterone, hydrocortisone, peptide yy, leptin, blood glucose, caloric restriction, appetite, adolescent, adult, female, male, ghrelin, alpha-amylases, stress, physiological, young adult
2 authors
From US
- Mitchell E. ZaplatoschUniversity of North Carolina at Greensboro
- William M. Adams · correspondingUniversity of North Carolina at Greensboro
Abstract
Evidence synthesizing the effects of acute body water losses on various markers of glycemic regulation, appetite, metabolism, and stress is lacking. Thus, the purpose of this review was to summarize the response of various hormonal changes involved in these physiologic functions to dehydration. A comprehensive literature search for peer-reviewed research in the databases PubMed, Scopus, CINAHL, and SportDiscus was conducted. Studies were included if they contained samples of adults (>18 years) and experimentally induced dehydration as measured by acute body mass loss. Twenty-one articles were eligible for inclusion. Findings suggested cortisol is significantly elevated with hypohydration (standard mean difference [SMD] = 1.12, 95% CI [0.583, 1.67], p p = 0.02), however, there were no changes in testosterone in studies examining hypohydration alone (SMD = -0.17, 95% CI [-0.51 0.16], p = 0.30). Insulin and ghrelin were unaffected by acute total body water losses. Acute hypohydration increases markers of catabolism but has a negligible effect on markers of glycemic regulation, appetite, anabolism and stress. Given the brevity of existing research, further research is needed to determine the impact of hydration on glucagon, leptin, peptide YY and the subsequent outcomes relevant to both health and performance.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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