Meta-analysis2020Open access

Effects of music therapy on depression: A meta-analysis of randomized controlled trials

Tang Q, Huang Z, Zhou H, Ye P

PloS one · 71 citations

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding
Government
Ministry of Education of the People's Republic of China
Government
Research Project of Anhui Province Social Science Innovation Development
Government
Ministry of Education Humanities and Social Sciences Research Youth fund Project
Government
Key Project of University Humanities and Social Science Research in Anhui Province

Based on 4 listed funder(s) and full-text disclosure statement.

Publication

Published
2020-11-18 · PLoS One · vol. 15 · issue 11 · p. e0240862
Publisher
Public Library of Science
Cited
151 citations · more than 86% of similar papers · 2.3× the field average
References
77 works
Access
Open access (journal) · CC-BY
Research areas
Music Therapy and Health · Art Therapy and Mental Health · Neuroscience and Music Perception
Keywords
Music therapy, Randomized controlled trial, Medicine, Meta-analysis, Internal medicine, Strictly standardized mean difference, MEDLINE, Cochrane Library, Depression (economics), Physical therapy
MeSH
humans, treatment outcome, music therapy, depression, time factors, female, male, randomized controlled trials as topic

4 authors

From CN

  • Qishou TangBengbu Medical College
  • Zhaohui HuangAnhui Provincial Center for Disease Control and Prevention
  • Huan ZhouBengbu Medical College; First Affiliated Hospital of Bengbu Medical College
  • Peijie Ye · correspondingBengbu Medical College

Abstract

Background

We aimed to determine and compare the effects of music therapy and music medicine on depression, and explore the potential factors associated with the effect.

Methods

PubMed (MEDLINE), Ovid-Embase, the Cochrane Central Register of Controlled Trials, EMBASE, Web of Science, and Clinical Evidence were searched to identify studies evaluating the effectiveness of music-based intervention on depression from inception to May 2020. Standardized mean differences (SMDs) were estimated with random-effect model and fixed-effect model.

Results

A total of 55 RCTs were included in our meta-analysis. Music therapy exhibited a significant reduction in depressive symptom (SMD = -0.66; 95% CI = -0.86 to -0.46; P<0.001) compared with the control group; while, music medicine exhibited a stronger effect in reducing depressive symptom (SMD = -1.33; 95% CI = -1.96 to -0.70; P<0.001). Among the specific music therapy methods, recreative music therapy (SMD = -1.41; 95% CI = -2.63 to -0.20; P<0.001), guided imagery and music (SMD = -1.08; 95% CI = -1.72 to -0.43; P<0.001), music-assisted relaxation (SMD = -0.81; 95% CI = -1.24 to -0.38; P<0.001), music and imagery (SMD = -0.38; 95% CI = -0.81 to 0.06; P = 0.312), improvisational music therapy (SMD = -0.27; 95% CI = -0.49 to -0.05; P = 0.001), music and discuss (SMD = -0.26; 95% CI = -1.12 to 0.60; P = 0.225) exhibited a different effect respectively. Music therapy and music medicine both exhibited a stronger effects of short and medium length compared with long intervention periods.

Conclusions

A different effect of music therapy and music medicine on depression was observed in our present meta-analysis, and the effect might be affected by the therapy process.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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