Current application and future directions of photobiomodulation in central nervous diseases
Yang M, Yang Z, Wang P, Sun Z
Neural regeneration research · 39 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Systematic review (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2020-12-03 · Neural Regen Res · vol. 16 · issue 6 · p. 1177
- Publisher
- Medknow
- Cited
- 55 citations · more than 91% of similar papers · 2.3× the field average
- Impact
- Top 10% most cited in its field
- References
- 111 works
- Access
- Open access (journal) · CC-BY-NC-SA
- Research areas
- Laser Applications in Dentistry and Medicine · Medical and Biological Ozone Research · Acupuncture Treatment Research Studies
- Keywords
- Medicine, Disease, Central nervous system, Cochrane Library, Stroke (engine), Bioinformatics, Intensive care medicine, Neuroscience, Physical medicine and rehabilitation, Pathology, Internal medicine, Alternative medicine
4 authors
From CN
- Pu WangSun Yat-sen University; Shanghai Jiao Tong University; The Seventh Affiliated Hospital of Sun Yat-sen University
- Zhihui SunSichuan University; West China Hospital of Sichuan University; The Fifth People’s Hospital of Suzhou
- Muyue YangSun Yat-sen University; Shanghai Jiao Tong University; The Seventh Affiliated Hospital of Sun Yat-sen University
- Zhen YangSichuan University; West China Hospital of Sichuan University; The Fifth People’s Hospital of Suzhou
Abstract
Photobiomodulation using light in the red or near-infrared region is an innovative treatment strategy for a wide range of neurological and psychological conditions. Photobiomodulation can promote neurogenesis and elicit anti-apoptotic, anti-inflammatory and antioxidative responses. Its therapeutic effects have been demonstrated in studies on neurological diseases, peripheral nerve injuries, pain relief and wound healing. We conducted a comprehensive literature review of the application of photobiomodulation in patients with central nervous system diseases in February 2019. The NCBI PubMed database, EMBASE database, Cochrane Library and ScienceDirect database were searched. We reviewed 95 papers and analyzed. Photobiomodulation has wide applicability in the treatment of stroke, traumatic brain injury, Parkinson's disease, Alzheimer's disease, major depressive disorder, and other diseases. Our analysis provides preliminary evidence that PBM is an effective therapeutic tool for the treatment of central nervous system diseases. However, additional studies with adequate sample size are needed to optimize treatment parameters.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-SA).
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