Study2020Open access

Egg consumption and health outcomes: a global evidence mapping based on an overview of systematic reviews

Zhang X, Lv M, Luo X, Estill J, Wang L, Ren M, Liu Y, Feng Z, Wang J, Wang X, Chen Y

Annals of translational medicine · 6 citations

How it was studied

Design
Systematic review (classified by our AI screen)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Not stated

Who paid for it

Funding
Independent funding
University or hospital
Lanzhou University

Based on 1 listed funder(s).

Publication

Published
2020-11-01 · Ann Transl Med · vol. 8 · issue 21 · p. 1343
Publisher
AME Publishing Company
Cited
12 citations · more than 51% of similar papers · 0.4× the field average
References
61 works
Access
Open access (free to publish) · CC-BY-NC-ND
Research areas
Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Agriculture Sustainability and Environmental Impact
Keywords
Systematic review, Medicine, Meta-analysis, Quality of evidence, MEDLINE, Consumption (sociology), Quality (philosophy), Environmental health, Pathology, Biology

11 authors

From CN, CH

  • Xianzhuo ZhangLanzhou University
  • Meng LvLanzhou University
  • Xufei LuoLanzhou University
  • Janne Anton Markus EstillUniversity of Geneva; University of Bern
  • Ling WangLanzhou University
  • Mengjuan RenLanzhou University

Abstract

Background

Several systematic reviews and meta-analyses have assessed the association between egg consumption and human health, but the evidence is often conflicting.

Methods

We conducted a systematic literature search to find all systematic reviews and meta-analyses that assess the association between egg consumption and any type of health outcome. We used AMSTAR to evaluate the methodological quality of the reviews, and GRADE to determine the quality of evidence. We visualized the results using a human anatomy diagram and evidence mapping.

Results

Our search revealed 29 systematic reviews and meta-analyses. Eight studies were of high methodological quality, 16 studies of medium quality, and five studies of low quality. We identified 34 primary outcomes from the included 29 reviews, which were combined into a total of 22 different health outcomes. Two of the primary outcomes were based on high-quality evidence, 18 on moderate-quality evidence, and 14 on low-quality evidence. Egg consumption was associated with an increased risk of two diseases and decreased risk of six outcomes. For ten outcomes, no significant association was found, and for four outcomes, different reviews came to conflicting conclusions.

Conclusions

The association between egg consumption and the risk of cancer, diabetes, cardiovascular diseases and other related diseases has been studied in several meta-analyses. The evidence from different studies on the same topic was often conflicting, which can complicate the making of dietary recommendations.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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