Association of Magnesium Intake with Liver Fibrosis among Adults in the United States
Tao MH, Fulda KG
Nutrients · 14 citations
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Institute on Minority Health and Health Disparities
- Government
- NIMHD NIH HHS
- Grants
- National Institute on Minority Health and Health Disparities (U54MD006882)
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-01-02 · Nutrients · vol. 13 · issue 1 · p. 142
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 23 citations · more than 85% of similar papers · 1.9× the field average
- References
- 51 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Liver Disease Diagnosis and Treatment · Magnesium in Health and Disease · Pancreatitis Pathology and Treatment
- Keywords
- Medicine, Magnesium, Fibrosis, Association (psychology), Gastroenterology, Internal medicine, Liver fibrosis, Environmental health, Physiology, Chemistry, Psychology
- MeSH
- liver, humans, liver cirrhosis, magnesium deficiency, calcium, magnesium, nutrition surveys, prevalence, alcohol drinking, nutritional status, eating, adult, middle aged, united states, female, male
2 authors
From US
- Meng‐Hua Tao · correspondingUniversity of North Texas; University of North Texas Health Science Center
- Kimberly G. FuldaUniversity of North Texas; University of North Texas Health Science Center
Abstract
Liver fibrosis represents the consequences of chronic liver injury. Individuals with alcoholic or nonalcoholic liver diseases are at high risk of magnesium deficiency. This study aimed to evaluate the association between magnesium and calcium intakes and significant liver fibrosis, and whether the associations differ by alcohol drinking status. Based on the National Health and Nutrition Examination Survey (NHANES) 2017-2018, the study included 4166 participants aged >18 years who completed the transient elastography examination and had data available on magnesium intake. The median liver stiffness of 8.2 kPa was used to identify subjects with significant fibrosis (≥F2). The age-adjusted prevalence of significant fibrosis was 12.81%. Overall total magnesium intake was marginally associated with reduced odds of significant fibrosis (p trend = 0.14). The inverse association of total magnesium intake with significant fibrosis was primarily presented among those who had daily calcium intake <1200 mg. There were no clear associations for significant fibrosis with calcium intake. Findings suggest that high total magnesium alone may reduce risk of significant fibrosis. Further studies are needed to confirm these findings.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.