The effects of local versus systemic passive heating on the acute inflammatory, vascular and glycaemic response
Hoekstra SP, Ogawa T, Dos Santos M, Handsley G, Bailey SJ, Goosey-Tolfrey VL, Tajima F, Cheng JL, Leicht CA
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 22 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2021-01-13 · Appl Physiol Nutr Metab · vol. 46 · issue 7 · pp. 808–818
- Publisher
- NRC Research Press
- Cited
- 24 citations · more than 79% of similar papers · 1.4× the field average
- References
- 60 works
- Access
- Open access (repository copy)
- Research areas
- Thermoregulation and physiological responses · Infrared Thermography in Medicine · Exercise and Physiological Responses
- Keywords
- Medicine, Blood flow, Area under the curve, Thermoregulation, Femoral artery, Internal medicine, Anesthesia, Cardiology
- MeSH
- lower extremity, femoral artery, humans, inflammation, nitrites, blood glucose, interleukin-6, area under curve, perception, body temperature regulation, regional blood flow, adult, male, interleukin 1 receptor antagonist protein, cold temperature, hot temperature, young adult
9 authors
From GB, JP, CA
- Sven P. HoekstraLoughborough University; Wakayama Medical University
- Takahiro OgawaWakayama Medical University
- Miguel Antônio Oliveira SantosLoughborough University
- Greg HandsleyLoughborough University
- Stephen J. BaileyLoughborough University
- Victoria Louise Goosey-TolfreyLoughborough University
Abstract
The aim of this study was to compare the acute cardiometabolic and perceptual responses between local and whole-body passive heating. Using a water-perfused suit, 10 recreationally active males underwent three 90 min conditions: heating of the legs with upper-body cooling (LBH), whole-body heating (WBH) and exposure to a thermoneutral temperature (CON). Blood samples were collected before and up to 3 h post-session to assess inflammatory markers, while a 2 h oral glucose tolerance test was initiated 1 h post-session. Femoral artery blood flow and perceptual responses were recorded at regular intervals. The interleukin (IL)-6 incremental area under the curve (iAUC) was higher for LBH (1096 ± 851 pg/mL × 270 min) and WBH (833 ± 476 pg/mL × 270 min) compared with CON (565 ± 325 pg/mL × 270 min; p p p p = 0.002). Affect and thermal comfort were more negative during WBH compared with LBH and CON (p Novelty: The increase in the IL-6 iAUC in response to passive heating is not reduced by upper-body cooling. Upper-body cooling attenuates the plasma nitrite, IL-1ra and femoral artery blood flow response to passive heating. Upper-body cooling leads to more positive perceptual responses to passive heating.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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