Effects of cold water immersion on circulating inflammatory markers at the Kona Ironman World Championship
Bartley JM, Stearns RL, Muñoz CX, Nolan JK, Radom-Aizik S, Maresh CM, Casa DJ, Zaldivar FP, Haddad F, Ganio M, Lee EC
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme · 6 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2021-01-28 · Appl Physiol Nutr Metab · vol. 46 · issue 7 · pp. 719–726
- Publisher
- NRC Research Press
- Cited
- 7 citations · more than 58% of similar papers · 0.3× the field average
- References
- 44 works
- Access
- Paywalled
- Research areas
- Exercise and Physiological Responses · Thermoregulation and physiological responses · Muscle metabolism and nutrition
- Keywords
- Muscle damage, Inflammation, Creatine kinase, Championship, Medicine, Internal medicine, Immunology
- MeSH
- humans, inflammation, cytokines, erythrocyte count, leukocyte count, immersion, competitive behavior, physical endurance, running, swimming, sports, bicycling, adult, middle aged, female, male, cold temperature, myalgia
11 authors
From US
- Jenna M. BartleyUniversity of Connecticut; UConn Health
- Rebecca L. StearnsUniversity of Connecticut
- Colleen X. MuñozUniversity of Connecticut
- Julie K. NolanUniversity of Connecticut
- Shlomit Radom‐AizikUniversity of California, Irvine; Irvine University
- Carl M. MareshThe Ohio State University
Abstract
Cold water immersion (CWI) purportedly reduces inflammation and improves muscle recovery after exercise, yet its effectiveness in specific contexts (ultraendurance) remains unclear. Thus, our aim was to study hematological profiles, systemic inflammation, and muscle damage responses to a specific post-race CWI (vs. control) during recovery after the Ironman World Championship, a culmination of ∼100 000 athletes competing in global qualifying Ironman events each year. Twenty-nine competitors were randomized into either a CWI or control (CON) group. Physiological parameters and blood samples were taken at pre-race, after intervention (POST), and 24 (+1DAY) and 48 hours (+2DAY) following the race. Muscle damage markers (plasma myoglobin, serum creatine kinase) were elevated at POST, +1DAY, and +2DAY, while inflammatory cytokines interleukin (IL)-6, IL-8, and IL-10 and total leukocyte counts were increased only at POST. CWI had no effect on these markers. Numbers of the most abundant circulating cell type, neutrophils, were elevated at POST more so in CWI (p Novelty: Ironman World Championship event increased circulating muscle damage markers, inflammatory markers, and hematological parameters, including circulating immune cell sub-populations that recover 24-48 hours after the race. 12-min CWI post-ultraendurance event affects the absolute numbers of neutrophils acutely, post-race (vs. CON), but does not impact recovery 24- and 48-hours post-race.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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