Time restricted eating as a weight loss intervention in adults with obesity
Przulj D, Ladmore D, Smith KM, Phillips-Waller A, Hajek P
PloS one · 30 citations
How it was studied
- Design
- Controlled clinical trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Nonprofit
- British Heart Foundation
- Grants
- British Heart Foundation (PG/17/41/33038)
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-01-28 · PLoS One · vol. 16 · issue 1 · p. e0246186
- Publisher
- Public Library of Science
- Cited
- 40 citations · more than 94% of similar papers · 3.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 33 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Enhanced Recovery After Surgery · Circadian rhythm and melatonin
- Keywords
- Medicine, Weight loss, Obesity, Weight management, Cohort, Lipid profile, Internal medicine, Cholesterol
- MeSH
- humans, obesity, weight loss, chronotherapy, prospective studies, pilot projects, adult, middle aged, female, male
5 authors
From GB
- Dunja Przulj · correspondingQueen Mary University of London
- Daniella LadmoreQueen Mary University of London
- Katie Myers SmithQueen Mary University of London
- Anna Phillips‐WallerQueen Mary University of London
- Peter HájekQueen Mary University of London
Abstract
Objectives
Time-restricted eating (TRE) is a weight management approach in which food is consumed only within a specific period each day. The simplicity of this approach is appealing, but its efficacy is not known. The aim of this pilot cohort study was to assess adherence to TRE and its effects on weight and lipid profile.
Methods
Fifty participants with obesity attempted to follow TRE for 12 weeks. Surveys were conducted weekly over the phone to assess treatment adherence and ratings; and at 6 and 12 weeks, participants attended the clinic to be weighed, have their blood pressure taken and provide a blood sample for lipid profile. Treatment results were compared with data from previous comparable cohorts using other weight management methods.
Results
Mean age of the participants was 50 (SD = 12.0), mean weight 97kg (SD = 17.1), mean BMI = 35 (SD = 4.0) and most were female (74%). At weeks 6 and 12, 64% and 58% of participants continued to practice TRE on at least five days/week. Using the 'last observation carried forward' imputation, mean (SD) weight loss was 2.0 (1.7) kg and 2.6 (2.6) kg at 6 and 12 weeks. Among participants who provided follow-up data, those who adhered to the intervention for at least five days/week recorded greater weight loss than those with lower adherence (week 6: 2.5 (1.7) vs 1.0 (1.3), p = 0.003; week 12: 3.5 (2.7) vs 1.3 (2.0), p = 0.001). A total of 26% of the sample lost at least 5% of their body weight at 12 weeks. The intervention had no effect on blood pressure or lipid profile.
Conclusions
TRE results were modest, but at least on par with those achieved with more complex interventions, and weight loss did not decline at 12 weeks. A formal trial of the intervention is warranted.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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