Effect of dietary nitrate ingestion on muscular performance: a systematic review and meta-analysis of randomized controlled trials
Alvares TS, Oliveira GV, Volino-Souza M, Conte-Junior CA, Murias JM
Critical reviews in food science and nutrition · 18 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro
- Government
- Natural Sciences and Engineering Research Council of Canada
- Government
- FAPERJ
- Government
- NSERC
- Government
- Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro
- Nonprofit
- Heart and Stroke Foundation of Canada National New Investigator Salary Award
- Grants
- Natural Sciences and Engineering Research Council of Canada (rgpin-2016-03698); Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (E-02/2019BPDE-02/2019); Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (E-26/202.905/2019)
Based on 6 listed funder(s).
Publication
- Published
- 2021-02-08 · Crit Rev Food Sci Nutr · vol. 62 · issue 19 · pp. 5284–5306
- Publisher
- Taylor & Francis
- Cited
- 22 citations · more than 76% of similar papers · 1.4× the field average
- References
- 64 works
- Access
- Paywalled
- Research areas
- Cardiovascular and exercise physiology · Muscle metabolism and nutrition · Exercise and Physiological Responses
- Keywords
- Ingestion, Physical strength, Isometric exercise, Meta-analysis, Medicine, Physical therapy, Endurance training, Internal medicine
- MeSH
- nitrates, exercise, eating, muscle strength, randomized controlled trials as topic
5 authors
From BR, CA
- Thiago Silveira Álvares · correspondingUniversidade Federal do Rio de Janeiro
- Gustavo Vieira de OliveiraUniversidade Federal do Rio de Janeiro
- Mônica Volino‐SouzaUniversidade Federal do Rio de Janeiro
- Carlos Adam Conte‐JúniorUniversidade Federal do Rio de Janeiro
- Juan Manuel MuriasUniversity of Calgary
Abstract
Dietary nitrate consumption from foods such as beetroot has been associated with many physiological benefits including improvements in vascular health and exercise performance. More recently, attention has been given to the use of dietary nitrate as a nutritional strategy to optimize muscular performance during resistance exercise. Our purpose was to perform a systematic review and meta-analysis of the research literature assessing the effect of dietary nitrate ingestion on muscular strength and muscular endurance. A structured search was carried out in accordance with PRISMA guidelines and from the total included studies (n = 34 studies), 12 studies had data for both measurement of strength and muscular endurance outcomes, 14 studies had data only for muscular strength outcome, and 8 studies had data only for muscular endurance outcome. Standardized mean difference (SMD) was calculated and meta-analyses were performed by using a random-effects model. Dietary nitrate ingestion was found to result in a trivial but significant effect on muscular strength (overall SMD = 0.08, P = 0.0240). Regarding muscular endurance dietary nitrate was found to promote a small but significant effect (overall SMD = 0.31, P < 0.0001). Dosage, frequency of ingestion, training level, muscle group, or type of contraction did not affect the findings, except for a greater improvement in muscle endurance during isometric and isotonic when compared to isokinetic contractions. Dietary nitrate seems to have a positive effect on muscular strength and muscular endurance, which is mostly unaffected by dosage, frequency of ingestion, training level, muscle group, or type of contraction. However, given the trivial to small effect, further experimental research on this topic is warranted.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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