Effective Connectivity During Rest and Music Listening: An EEG Study on Parkinson's Disease
Maggioni E, Arienti F, Minella S, Mameli F, Borellini L, Nigro M, Cogiamanian F, Bianchi AM, Cerutti S, Barbieri S, Brambilla P, Ardolino G
Frontiers in aging neuroscience · 13 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Case-control study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
Who paid for it
- Funding
- Independent funding
- Government
- Ministero della Salute
- Grants
- Ministero della Salute (GR‐2018‐12367789); Ministero della Salute (2018-); Ministero della Salute (RF‐2016‐02364582); Ministero della Salute (02364582)
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-04-28 · Front Aging Neurosci · vol. 13 · p. 657221
- Publisher
- Frontiers Media
- Cited
- 26 citations · more than 83% of similar papers · 1.7× the field average
- References
- 68 works
- Access
- Open access (journal) · CC-BY
- Research areas
- EEG and Brain-Computer Interfaces · Neural dynamics and brain function · Neuroscience and Neural Engineering
- Keywords
- Electroencephalography, Psychology, Active listening, Audiology, Rhythm, Neuroscience, Resting state fMRI, Parkinson's disease, Alpha (finance), Cognitive psychology, Medicine, Disease, Communication, Developmental psychology, Internal medicine
12 authors
From IT
- Eleonora MaggioniFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Federica ArientiUniversity of Milan
- Stella MinellaFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Francesca MameliFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Linda BorelliniFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
- Martina NigroFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
Abstract
Music-based interventions seem to enhance motor, sensory and cognitive functions in Parkinson's disease (PD), but the underlying action mechanisms are still largely unknown. This electroencephalography (EEG) study aimed to investigate the effective connectivity patterns characterizing PD in the resting state and during music listening. EEG recordings were obtained from fourteen non-demented PD patients and 12 healthy controls, at rest and while listening to three music tracks. Theta- and alpha-band power spectral density and multivariate partial directed coherence were computed. Power and connectivity measures were compared between patients and controls in the four conditions and in music vs. rest. Compared to controls, patients showed enhanced theta-band power and slightly enhanced alpha-band power, but markedly reduced theta- and alpha-band interactions among EEG channels, especially concerning the information received by the right central channel. EEG power differences were partially reduced by music listening, which induced power increases in controls but not in patients. Connectivity differences were slightly compensated by music, whose effects largely depended on the track. In PD, music enhanced the frontotemporal inter-hemispheric communication. Our findings suggest that PD is characterized by enhanced activity but reduced information flow within the EEG network, being only partially normalized by music. Nevertheless, music capability to facilitate inter-hemispheric communication might underlie its beneficial effects on PD pathophysiology and should be further investigated.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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