Time-Restricted Feeding and Metabolic Outcomes in a Cohort of Italian Adults
Currenti W, Buscemi S, Cincione RI, Cernigliaro A, Godos J, Grosso G, Galvano F
Nutrients · 29 citations
How it was studied
- Design
- Cross-sectional study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2021-05-13 · Nutrients · vol. 13 · issue 5 · p. 1651
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 32 citations · more than 89% of similar papers · 2.4× the field average
- References
- 71 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Genetics, Aging, and Longevity in Model Organisms · Circadian rhythm and melatonin
- Keywords
- Cohort, Medicine, Biology, Physiology, Internal medicine
- MeSH
- humans, hypertension, diabetes mellitus, type 2, obesity, fasting, nutrition assessment, cross-sectional studies, feeding behavior, diet, mediterranean, time factors, adult, middle aged, italy, female, male, dyslipidemias
7 authors
From IT
- Walter CurrentiUniversity of Catania
- Silvio BuscemiUniversity of Palermo
- Raffaele Ivan CincioneUniversity of Foggia
- Achille CernigliaroRegione Siciliana
- Justyna GodosUniversity of Catania
- Giuseppe Grosso · correspondingUniversity of Catania
Abstract
Background
research exploring the effects of food timing and frequency on health and disease is currently ongoing. While there is an increasing body of scientific literature showing the potential health benefits of intermittent fasting (IF) in laboratory settings and in animals, studies regarding IF on humans are limited. Therefore, the objective of this research was to evaluate the relationship between the feeding/fasting time window and metabolic outcomes among adult individuals.
Methods
dietary and demographic data of 1936 adult subjects living in the south of Italy were examined. Food frequency questionnaires (FFQ) were administered to determine the period of time between the first and the last meal of a typical day. Subjects were then divided into those with a time feeding window lasting more than 10 h, within 8 h (TRF-8) and within 10 h.
Results
after adjustment for potential confounding factors related to eating habits (such as adherence to the Mediterranean diet, having breakfast/dinner), TRF-10 was inversely associated with being overweight/obese (OR = 0.05, 95% CI: 0.01, 0.07), hypertension (OR = 0.24, 95% CI: 0.13, 0.45), and dyslipidemias (OR = 0.26, 95% CI: 0.10, 0.63), while TRF-8 only with being overweight/obese (OR = 0.08, 95% CI: 0.04, 0.15) and hypertension (OR = 0.33, 95% CI: 0.17, 0.60). No associations were found with type-2 diabetes.
Conclusions
individuals with a restricted feeding time window were less likely to be overweight, obese and hypertensive. Further studies are needed to clearly validate the results of the present study.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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