Meta-analysis2023

Ultra-processed food consumption and adult obesity risk: a systematic review and dose-response meta-analysis

Moradi S, Entezari MH, Mohammadi H, Jayedi A, Lazaridi AV, Kermani MAH, Miraghajani M

Critical reviews in food science and nutrition · 108 citations

Review labels

Funding not disclosed

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Not stated

Who paid for it

Funding
Funding not disclosed

Publication

Published
2021-06-30 · Crit Rev Food Sci Nutr · vol. 63 · issue 2 · pp. 249–260
Publisher
Taylor & Francis
Cited
153 citations · more than 97% of similar papers · 5.6× the field average
Impact
Top 10% most cited in its field
References
54 works
Access
Paywalled
Research areas
Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Obesity, Physical Activity, Diet
Keywords
Medicine, Overweight, Obesity, Meta-analysis, Abdominal obesity, Odds ratio, Population, Cohort study, Internal medicine, Environmental health, Metabolic syndrome
MeSH
humans, cross-sectional studies, adult, obesity, abdominal, observational studies as topic, food, processed

7 authors

From IR, GB

  • Sajjad MoradiIsfahan University of Medical Sciences
  • Mohammad Hassan Entezari · correspondingIsfahan University of Medical Sciences
  • Hamed MohammadiTehran University of Medical Sciences
  • Ahmad JayediTehran University of Medical Sciences
  • Anastasia-Viktoria LazaridiUniversity of Nottingham
  • Mohammad Ali Hojjati KermaniMasih Daneshvari Hospital; Shahid Beheshti University of Medical Sciences

Abstract

We performed this systematic review and meta-analysis to evaluate observational studies assessing the association between ultra-processed food (UPF) consumption and the risk of overweight, obesity, and abdominal obesity in the general population. We searched the databases PubMed/MEDLINE, Scopus, Embase, and ISI Web of Science from inception until December 2020. Data were extracted from 12 studies (nine cross-sectional and three cohort studies). Odds ratio (OR) were pooled using a random-effects model. UPF consumption was associated with an increased risk of obesity (OR = 1.55; 95% CI: 1.36, 1.77; I2 = 55%), overweight (OR = 1.36; 95% CI: 1.14, 1.63; I2 = 73%), and abdominal obesity (OR = 1.41; 95% CI: 1.18, 1.68; I2 = 62%). Furthermore, every 10% increase of UPF consumption in daily calorie intake was associated with a 7%, a 6%, and a 5% higher risk of overweight, obesity, and abdominal obesity, respectively. Dose-response meta-analysis of cross-sectional studies showed a positive linear association between UPF consumption and abdominal obesity. There was also a positive linear association between UPF consumption and risk of overweight/obesity in the analysis of cross-sectional studies and a positive monotonic association in the analysis of cohort studies. Our study suggests that UPF consumption is associated with an increased risk of excess weight or abdominal obesity.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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