The effects of dietary nitrate supplementation on endurance exercise performance and cardiorespiratory measures in healthy adults: a systematic review and meta-analysis
Gao C, Gupta S, Adli T, Hou W, Coolsaet R, Hayes A, Kim K, Pandey A, Gordon J, Chahil G, Belley-Cote EP, Whitlock RP
Journal of the International Society of Sports Nutrition · 34 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Nonprofit
- Heart and Stroke Foundation of Canada
- Authors
- At least one author declares a financial tie to industry
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-01-02 · J Int Soc Sports Nutr · vol. 18 · issue 1 · p. 55
- Publisher
- Springer Science+Business Media
- Cited
- 53 citations · more than 80% of similar papers · 1.3× the field average
- References
- 25 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nitric Oxide and Endothelin Effects · Exercise and Physiological Responses · Muscle metabolism and nutrition
- Keywords
- Medicine, Cardiorespiratory fitness, Meta-analysis, Placebo, CINAHL, Physical therapy, Endurance training, Sports medicine, Time trial, Randomized controlled trial, Internal medicine, Strictly standardized mean difference, Blood pressure, Heart rate, Psychological intervention, Alternative medicine, Pathology
- MeSH
- humans, nitrates, lactic acid, oxygen consumption, physical endurance, exercise tolerance, time factors, dietary supplements, publication bias, adult, athletic performance, athletes, cardiorespiratory fitness, bias, sedentary behavior
12 authors
From CA
- Chloe GaoUniversity of British Columbia
- Saurabh Kumar GuptaMcMaster University Medical Centre; McMaster University
- Taranah AdliWestern University
- Winston HouMcMaster University Medical Centre; Hamilton Health Sciences; McMaster University
- Reid CoolsaetUniversity of Guelph
- Abigail HayesQueen's University
Abstract
Background
Nitrate supplementation is thought to improve performance in endurance sports.
Objective
To meta-analyze studies evaluating the effect of nitrate supplementation on endurance sports performance among adults.
Data sources
We searched the Cochrane Central Register of Controlled Trials (CENTRAL), MEDLINE, EMBASE, Web of Science and CINAHL without language restrictions.
Methods
We included studies that: 1) compared nitrate supplementation with placebo; 2) enrolled adults engaging in an endurance-based activity; and 3) reported a performance measure or surrogate physiologic outcome. We evaluated risk of bias using the Cochrane Collaboration tool and pooled data with a random-effects model. We used the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach to evaluate confidence in estimates.
Results
We included 73 studies (n = 1061). Nitrate supplementation improved power output (MD 4.6 watts, P 2 (MD - 0.04 L/min, P 2max or blood lactate levels.
Conclusion
The available evidence suggests that dietary nitrate supplementation benefits performance-related outcomes for endurance sports.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.