Effect of a Nutritionally Balanced Diet Comprising Whole Grains and Vegetables Alone or in Combination with Probiotic Supplementation on the Gut Microbiota
Oh YJ, Nam K, Kim Y, Lee SY, Kim HS, Kang JI, Lee SY, Hwang KT
Preventive nutrition and food science · 9 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Authors
- At least one author declares a financial tie to industry
Based on full-text disclosure statement.
Publication
- Published
- 2021-06-30 · Prev Nutr Food Sci · vol. 26 · issue 2 · pp. 121–131
- Publisher
- Korean Society of Food Science and Nutrition
- Cited
- 12 citations · more than 54% of similar papers · 0.4× the field average
- References
- 47 works
- Access
- Open access (hybrid journal) · CC-BY-NC
- Research areas
- Gut microbiota and health · Gastrointestinal motility and disorders · Probiotics and Fermented Foods
- Keywords
- Probiotic, Gut flora, Food science, Biology, Biotechnology, Chemistry, Bacteria, Biochemistry, Genetics
8 authors
From KR
- Young Joo OhSeoul National University
- Kisun Nam · corresponding
- Yanghee Kim
- Seo Yeon Lee
- Hyung Sook KimUniversity of Suwon
- Jung Il Kang
Abstract
Dysbiosis is a microbial imbalance, which often causes diseases and can be triggered by diet. Here, we deter-mined the effect of a nutritionally balanced diet rich in vegetables and whole grains alone and/or in combination with probiotics on the gut microbiota of healthy adults. We conducted a parallel-group randomized trial enrolling 63 healthy participants who were administered either a balanced diet (B-diet group), a probiotic capsule containing Lactobacillus plantarum PMO 08 (probiotics group), or a balanced diet plus probiotic capsule (synbiotics group) once daily for 2 weeks. The gut microbiota of each participant was analyzed via 16S ribosomal RNA MiSeq-based sequencing. Gastrointestinal symptoms and defecation habits were evaluated using questionnaires. The B-diet group showed significantly reduced Firmicutes-to-Bacteroidetes ratio (PBlautia (PDorea (PLachnoclostridium (PBacteroides increased (PLactobacillus abundance increased significantly (PPPPFaecalibacterium significantly increased in the probiotics group (PL. plantarum PMO 08 beneficially modifies the gut microbiota with the potential to alleviate gastrointestinal symptoms and improve defecation habits.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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