Randomized controlled trial2021Open access

Comparative Efficacy of Active Group Music Intervention versus Group Music Listening in Alzheimer's Disease

Gómez-Gallego M, Gómez-Gallego JC, Gallego-Mellado M, García-García J

International journal of environmental research and public health · 48 citations

How it was studied

Design
Randomized controlled trial (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2021-07-30 · Int J Environ Res Public Health · vol. 18 · issue 15 · p. 8067
Publisher
Multidisciplinary Digital Publishing Institute
Cited
91 citations · more than 99% of similar papers · 9.9× the field average
Impact
Top 10% most cited in its field
References
59 works
Access
Open access (journal) · CC-BY
Research areas
Music Therapy and Health · Dementia and Cognitive Impairment Research · Neuroscience and Music Perception
Keywords
Psychological intervention, Active listening, Music therapy, Intervention (counseling), Disease, Psychology, Medicine, Psychiatry, Communication, Internal medicine
MeSH
humans, alzheimer disease, music therapy, activities of daily living, music, nursing homes

4 authors

From ES

  • María Gómez-Gallego · correspondingUniversidad Católica de Murcia
  • Juan Cándido Gómez‐GallegoUniversidad de Murcia
  • María Gallego-Mellado
  • Javier García‐GarcíaUniversidad de Murcia

Abstract

Background

Music interventions are promising therapies for the management of symptoms in Alzheimer's disease (AD). Globally, music interventions can be classified as active or receptive depending on the participation of the subjects. Active and receptive music tasks engage different brain areas that might result in distinctive clinical effects. This study aims to compare the clinical effects of two types of music interventions and a control activity.

Methods

Ninety AD patients from six nursing homes participated in the study. Nursing homes were randomly and blindly assigned to receive either active music intervention, receptive music intervention, or the usual care. Effects on cognition, behaviour, daily living activities, and motor function were assessed.

Results

Active music intervention improved cognition, behaviour, and functional state in a higher extent than both receptive music intervention and usual care. The effect size of active music intervention for cognitive deficits and behavioural symptoms was large (η2 = 0.62 and 0.61, respectively), while for functional state, it was small-to-medium sized (η2 = 0.18). Receptive music intervention had a stabilizing effect on behavioural symptoms compared to control intervention (mean change from baseline ± standard deviation = -0.76 ± 3.66 and 3.35 ± 3.29, respectively). In the active music intervention, the percentage of patients who showed improvement in cognitive deficits (85.7), behavioural symptoms (92.9), and functional state (46.4) was higher than in both receptive listening (11.8, 42.9, and 14.3, respectively) and control group (6.3, 12.2, and 17.1, respectively).

Conclusions

Active music intervention is useful to improve symptoms of AD and should be prescribed as a complement to the usual treatment.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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