Creatine Enhances the Effects of Cluster-Set Resistance Training on Lower-Limb Body Composition and Strength in Resistance-Trained Men: A Pilot Study
Bonilla DA, Kreider RB, Petro JL, Romance R, García-Sillero M, Benítez-Porres J, Vargas-Molina S
Nutrients · 22 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Possibly industry funded
- University or hospital
- University of Wales Trinity Saint David
- Authors
- At least one author declares a financial tie to industry
Based on 1 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-07-04 · Nutrients · vol. 13 · issue 7 · p. 2303
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 34 citations · more than 87% of similar papers · 2.1× the field average
- References
- 67 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Muscle metabolism and nutrition · Sports Performance and Training · Exercise and Physiological Responses
- Keywords
- Resistance training, Composition (language), Strength training, Physical medicine and rehabilitation, Resistance (ecology), Creatine, Cluster (spacecraft), Medicine, Physical therapy, Biology, Internal medicine, Computer science, Ecology
- MeSH
- lower extremity, muscle, skeletal, adipose tissue, humans, creatine, absorptiometry, photon, exercise, pilot projects, body composition, dietary supplements, adult, male, muscle strength, resistance training, young adult, performance-enhancing substances, diet, high-protein
7 authors
From ES, CO, US
- Diego A. Bonilla · correspondingUniversity of the Basque Country; University of Córdoba; Universidad Distrital Francisco José de Caldas
- Richard B. KreiderTexas A&M University
- Jorge Luis PetroUniversity of Córdoba
- Ramón RomanceUniversidad de Málaga
- Manuel García-Sillero
- Javier Benítez‐PorresUniversidad de Málaga
Abstract
Creatine monohydrate (CrM) supplementation has been shown to improve body composition and muscle strength when combined with resistance training (RT); however, no study has evaluated the combination of this nutritional strategy with cluster-set resistance training (CS-RT). The purpose of this pilot study was to evaluate the effects of CrM supplementation during a high-protein diet and a CS-RT program on lower-limb fat-free mass (LL-FFM) and muscular strength. Twenty-three resistance-trained men (>2 years of training experience, 26.6 ± 8.1 years, 176.3 ± 6.8 cm, 75.6 ± 8.9 kg) participated in this study. Subjects were randomly allocated to a CS-RT+CrM (n = 8), a CS-RT (n = 8), or a control group (n = 7). The CS-RT+CrM group followed a CrM supplementation protocol with 0.1 g·kg-1·day-1 over eight weeks. Two sessions per week of lower-limb CS-RT were performed. LL-FFM corrected for fat-free adipose tissue (dual-energy X-ray absorptiometry) and muscle strength (back squat 1 repetition maximum (SQ-1RM) and countermovement jump (CMJ)) were measured pre- and post-intervention. Significant improvements were found in whole-body fat mass, fat percentage, LL-fat mass, LL-FFM, and SQ-1RM in the CS-RT+CrM and CS-RT groups; however, larger effect sizes were obtained in the CS-RT+CrM group regarding whole body FFM (0.64 versus 0.16), lower-limb FFM (0.62 versus 0.18), and SQ-1RM (1.23 versus 0.75) when compared to the CS-RT group. CMJ showed a significant improvement in the CS-RT+CrM group with no significant changes in CS-RT or control groups. No significant differences were found between groups. Eight weeks of CrM supplementation plus a high-protein diet during a CS-RT program has a higher clinical meaningfulness on lower-limb body composition and strength-related variables in trained males than CS-RT alone. Further research might study the potential health and therapeutic effects of this nutrition and exercise strategy.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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