Cohort study2021Open access

Whole-Grain Intake in the Mediterranean Diet and a Low Protein to Carbohydrates Ratio Can Help to Reduce Mortality from Cardiovascular Disease, Slow Down the Progression of Aging, and to Improve Lifespan: A Review

Capurso C

Nutrients · 34 citations

Review labels

No stated lifestyle adjustment

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cohort study (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Not stated

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2021-07-25 · Nutrients · vol. 13 · issue 8 · p. 2540
Publisher
Multidisciplinary Digital Publishing Institute
Cited
59 citations · more than 97% of similar papers · 6.1× the field average
Impact
Top 10% most cited in its field
References
181 works
Access
Open access (journal) · CC-BY-NC-SA
Research areas
Nutritional Studies and Diet · Diet and metabolism studies · Nutrition and Health in Aging
Keywords
Mediterranean diet, Longevity, Life expectancy, Cohort, Medicine, Disease, Cohort study, Gerontology, Population, Physiology, Biology, Food science, Environmental health, Internal medicine
MeSH
humans, cardiovascular diseases, dietary carbohydrates, dietary proteins, diet, protein-restricted, diet, life expectancy, case-control studies, cohort studies, diet, mediterranean, aging, longevity, eating, middle aged, female, male, edible grain, whole grains, diet, carbohydrate loading

1 author

From IT

  • Cristiano A. Capurso · correspondingUniversity of Foggia

Abstract

Increase in the aging population is a phenomenon all over the world. Maintaining good functional ability, good mental health, and cognitive function in the absence of severe disease and physical disability define successful aging. A healthy lifestyle in middle age predisposes successful aging. Longevity is the result of a multifactorial phenomenon, which involves feeding. Diets that emphasize fruit and vegetables, whole grains rather than refined grains, low-fat dairy, lean meats, fish, legumes, and nuts are inversely associated with mortality or to a lower risk of becoming frail among elderly subjects. A regular physical activity and a regular intake of whole grain derivatives together with the optimization of the protein/carbohydrate ratio in the diet, where the ratio is significantly less than 1 such as in the Mediterranean diet and the Okinawan diet, reduces the risk of developing aging-related diseases and increases healthy life expectancy. The purpose of our review was to analyze cohort and case-control studies that investigated the effects of cereals in the diet, especially whole grains and derivatives as well as the effects of a diet with a low protein-carbohydrate ratio on the progression of aging, mortality, and lifespan.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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