Gut Microbiota Differences According to Ultra-Processed Food Consumption in a Spanish Population
Cuevas-Sierra A, Milagro FI, Aranaz P, Martínez JA, Riezu-Boj JI
Nutrients · 85 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Government
- Ministerio de Ciencia, Innovación y Universidades
- University or hospital
- Universidad de Navarra
- University or hospital
- Universitat Autònoma de Barcelona
- University or hospital
- Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición
- Government
- Gobierno de Navarra
- Grants
- Gobierno de Navarra (PI035); Gobierno de Navarra (0011-1411-2018-000040); Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición (CB12/03/30002); Ministerio de Ciencia, Innovación y Universidades (RTI2018-102205-B-I00); Gobierno de Navarra (PT024)
Based on 5 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-08-06 · Nutrients · vol. 13 · issue 8 · p. 2710
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 115 citations · more than 99% of similar papers · 13.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 81 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Culinary Culture and Tourism
- Keywords
- Bacteroidetes, Bifidobacterium, Actinobacteria, Biology, Food science, Gut flora, Population, Lactobacillus, Feces, Firmicutes, Clostridiaceae, Microbiology, 16S ribosomal RNA, Bacteria, Medicine, Immunology, Environmental health, Fermentation
- MeSH
- intestines, feces, humans, bacteria, diet, risk assessment, risk factors, sex factors, nutritive value, food handling, dairy products, adult, middle aged, spain, female, male, fast foods, dysbiosis, gastrointestinal microbiome
5 authors
From ES
- Amanda Cuevas‐SierraUniversidad de Navarra
- Fermin Ignacio Milagro · correspondingInstituto de Salud Carlos III; Navarre Institute of Health Research; Centro de Investigación Biomédica en Red; Universidad de Navarra
- Paula AranazUniversidad de Navarra
- J. Alfredo MartínézInstituto de Salud Carlos III; Navarre Institute of Health Research; Centro de Investigación Biomédica en Red; Universidad de Navarra
- José Ignacio Riezu‐BojNavarre Institute of Health Research; Universidad de Navarra
Abstract
Ultra-processed foods (UPFs) consumption could affect gut microbiota diversity and profile. We aimed to evaluate the effects of UPFs on microbiota, considering the role of sex. The consumption of UPFs (using NOVA criteria) was assessed with a validated 137-item food-frequency questionnaire. Participants (n = 359) were classified into less than three servings per day (n = 96) of UPFs and more than five (n = 90). Women and men were subclassified following the same criteria. 16S rRNA sequencing was performed from DNA fecal samples, and differences in microbiota were analyzed using EdgeR. The relationship between UPFs and bacteria was assessed by Spearman correlation and comparison of tertiles of consumption. Women who consumed more than five servings/day of UPFs presented an increase in Acidaminococcus, Butyrivibrio, Gemmiger, Shigella, Anaerofilum, Parabacteroides, Bifidobacterium, Enterobacteriales, Bifidobacteriales and Actinobacteria and a decrease in Melainabacter and Lachnospira. Bifidobacterium, Bifidobacteriales and Actinobacteria was positively associated with pizza and Actinobacteria with industrially processed dairy in women. Men who consumed more than five servings/day presented an increase of Granulicatella, Blautia, Carnobacteriaceae, Bacteroidaceae, Peptostreptococcaceae, Bacteroidia and Bacteroidetes and a decrease of Anaerostipes and Clostridiaceae. Bacteroidia and Bacteroidetes correlated positively with industrially processed meat. This study suggests that UPFs may affect microbiota composition differently in women and men.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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