Total and drinking water intake and risk of all-cause and cardiovascular mortality: A systematic review and dose-response meta-analysis of prospective cohort studies
Majdi M, Hosseini F, Naghshi S, Djafarian K, Shab-Bidar S
International journal of clinical practice · 11 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2021-09-15 · Int J Clin Pract · vol. 75 · issue 12 · p. e14878
- Publisher
- Wiley
- Cited
- 19 citations · more than 59% of similar papers · 0.6× the field average
- References
- 40 works
- Access
- Paywalled
- Research areas
- Sodium Intake and Health · Nutritional Studies and Diet · Thermoregulation and physiological responses
- Keywords
- Medicine, Meta-analysis, Prospective cohort study, Confidence interval, Cohort study, Relative risk, Cohort, Internal medicine
- MeSH
- humans, neoplasms, cardiovascular diseases, diet, risk factors, prospective studies, drinking, drinking water
5 authors
From IR
- Maryam MajdiTehran University of Medical Sciences
- Fatemeh Sadat HosseiniTehran University of Medical Sciences
- Sina NaghshiTehran University of Medical Sciences
- Kurosh DjafarianTehran University of Medical Sciences
- Sakineh Shab‐Bidar · correspondingTehran University of Medical Sciences
Abstract
Background
Understanding the association between water consumption and mortality is important for guiding consumers and prioritizing dietary guidelines to reduce the risk. Therefore, in the current study, we conducted a systematic review and dose-response meta-analysis of prospective cohort studies to summarise the association between total water and drinking intake and risk of mortality from all causes and CVD.
Method
A comprehensive search was performed on PubMed/Medline, Scopus, and ISI Web of Science up to February 2020. The random-effects model was used to calculate the pooled effect size (ES) and 95% confidence interval.
Result
Seven prospective cohort studies were included in the systematic review and meta-analysis. During the follow-up period of 6 to 19.1 years, 14 754 deaths (7611 from cardiovascular disease) occurred among 116 816 participants. No significant association was found between drinking water intake and all-cause mortality (ES: 0.82; 95% CI: 0.63-1.08, I2 = 77.3%, P = .16). Total water intake was not associated with all-cause mortality (ES: 0.94; 95% CI: 0.82-1.08, I2 = 66.5%, P = .41). However, a significant inverse association was seen between total water intake and risk of CVD mortality (ES: 0.86; 95% CI: 0.78-0.95, I2 = 0%, P = .002). Linear dose-response meta-analysis revealed a significant inverse association between total water intake and all-cause mortality by an additional one cup per day (pooled ES: 0.98; 95% CI: 0.97-0.99, P = .001). Furthermore, each additional cup of total water intake per day was associated with a 3% lower risk of death from CVD (pooled ES: 0.97; 95% CI: 0.96-0.98, P < .001).
Conclusion
High consumption of total water is associated with a lower risk of CVD mortality. However, total water intake was not associated with risk of all-cause mortality.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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