Intermittent Fasting and the Possible Benefits in Obesity, Diabetes, and Multiple Sclerosis: A Systematic Review of Randomized Clinical Trials
Morales-Suarez-Varela M, Collado Sánchez E, Peraita-Costa I, Llopis-Morales A, Soriano JM
Nutrients · 53 citations
How it was studied
- Design
- Systematic review (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2021-09-13 · Nutrients · vol. 13 · issue 9 · p. 3179
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 87 citations · more than 92% of similar papers · 2.5× the field average
- Impact
- Top 10% most cited in its field
- References
- 36 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Circadian rhythm and melatonin · Diet and metabolism studies
- Keywords
- Medicine, Intermittent fasting, Weight loss, Glycemic, Diabetes mellitus, Obesity, Multiple sclerosis, Randomized controlled trial, Clinical trial, Type 2 diabetes, Intensive care medicine, Internal medicine, Physical therapy, Endocrinology, Immunology
- MeSH
- humans, multiple sclerosis, diabetes mellitus, type 2, obesity, fasting, randomized controlled trials as topic, glycemic control
5 authors
From ES
- María Morales‐Suárez‐Varela · correspondingUniversitat de València; Instituto de Salud Carlos III; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
- Ester Collado SánchezUniversitat de València
- Isabel Peraita‐CostaUniversitat de València; Instituto de Salud Carlos III; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
- Agustín Llopis GonzálezUniversitat de València
- José Miguel SorianoUniversitat de València; Parc Científic de la Universitat de València; Instituto de Ciencia de Materiales de Sevilla; Instituto de Investigación Sanitaria La Fe
Abstract
Intermittent fasting has become popular in recent years and is controversially presented as a possible therapeutic adjunct. A bibliographic review of the literature on intermittent fasting and obesity, diabetes, and multiple sclerosis was carried out. The scientific quality of the methodology and the results obtained were evaluated in pairs. Intermittent fasting has beneficial effects on the lipid profile, and it is associated with weight loss and a modification of the distribution of abdominal fat in people with obesity and type 2 diabetes as well as an improvement in the control of glycemic levels. In patients with multiple sclerosis, the data available are too scarce to draw any firm conclusions, but it does appear that intermittent fasting may be a safe and feasible intervention. However, it is necessary to continue investigating its long-term effects since so far, the studies carried out are small and of short duration.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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