Cross-sectional study2021Industry fundedOpen access

Funded in part by American Egg Board

Egg intake moderates the rate of memory decline in healthy older adults

Lee GJ, Oda K, Morton KR, Orlich M, Sabate J

Journal of nutritional science · 10 citations

Review labels

Food frequency questionnaireIndustry fundedNo stated lifestyle adjustment

Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.

How it was studied

Design
Cross-sectional study (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Food frequency questionnaire

Who paid for it

Funding
Industry funded
Government
National Institute on Aging
Government
National Cancer Institute
Government
NIA NIH HHS
Government
NCI NIH HHS
Industry group
American Egg Board
Grants
National Cancer Institute (U01 CA152939); National Institute on Aging (R01 AG026348)

Based on 5 listed funder(s) and full-text disclosure statement.

Publication

Published
2021-01-01 · J Nutr Sci · vol. 10 · p. e79
Publisher
Cambridge University Press
Cited
15 citations · more than 86% of similar papers · 1.9× the field average
References
35 works
Access
Open access (journal) · CC-BY-NC-ND
Research areas
Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Obesity, Physical Activity, Diet
Keywords
California Verbal Learning Test, Medicine, Fish <Actinopterygii>, Cognitive decline, Body mass index, Demography, Verbal memory, Gerontology, Cognition, Biology, Internal medicine, Disease
MeSH
humans, memory disorders, diet, cross-sectional studies, cognition, eggs, aged, middle aged

5 authors

From US

  • Grace J. Lee · correspondingLoma Linda University
  • Keiji OdaLoma Linda University
  • Kelly R. MortonLoma Linda University
  • Michael J. OrlichLoma Linda University
  • Joan SabatéLoma Linda University

Abstract

Eggs contain important compounds related to enhanced cognition, but it is not clear if egg consumption, as a whole, has a direct impact on memory decline in older adults. This study aimed to determine whether egg intake levels predict the rate of memory decline in healthy older adults after sociodemographic and dietary controls. We conducted a secondary analysis of data from 470 participants, age 50 and over, from the Biospsychosocial Religion and Health Study. Participants completed a food frequency questionnaire, which was used to calculate egg intake and divide participants into Low (<23 g/week, about half an egg), Intermediate (24-63 g/week, half to 1½ eggs) and High (≥63 g/week, about two or more eggs) tertiles. Participants were administered the California Verbal Learning Test - 2nd Edition (CVLT-II) Short Form in 2006-2007, and 294 of them were again tested in 2010-2011. Using linear mixed model analysis, no significant cross-sectional differences were observed in CVLT-II performance between egg intake levels after controlling for age, sex, race, education, body mass index, cardiovascular risk, depression and intake of meat, fish, dairy and fruits/vegetables. Longitudinally, the Intermediate egg group exhibited significantly slower rates of decline on the CVLT-II compared to the Low egg group. The High egg group also exhibited slower rates of decline, but not statistically significant. Thus, limited consumption of eggs (about 1 egg/week) was associated with slower memory decline in late life compared to consuming little to no eggs, but a dose-response effect was not clearly evident. This study may help explain discrepancies in previous research that did not control for other dietary intakes and risk factors.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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