Processed and Unprocessed Red Meat Consumption and Risk for Type 2 Diabetes Mellitus: An Updated Meta-Analysis of Cohort Studies
Zhang R, Fu J, Moore JB, Stoner L, Li R
International journal of environmental research and public health · 31 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
Based on full-text disclosure statement.
Publication
- Published
- 2021-10-14 · Int J Environ Res Public Health · vol. 18 · issue 20 · p. 10788
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 47 citations · more than 84% of similar papers · 1.7× the field average
- References
- 62 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Biochemical Analysis and Sensing Techniques · Nutritional Studies and Diet · Meat and Animal Product Quality
- Keywords
- Type 2 Diabetes Mellitus, Medicine, Red meat, Meta-analysis, Cochrane Library, Confidence interval, Relative risk, Incidence (geometry), Cohort study, Type 2 diabetes, Insulin resistance, Diabetes mellitus, Internal medicine, Environmental health, Endocrinology, Pathology, Mathematics
- MeSH
- humans, diabetes mellitus, type 2, diet, incidence, risk factors, cohort studies, meat, meat products, red meat
5 authors
From CN, US
- Rui ZhangSouth Central Minzu University
- Jialin FuWuhan University
- Justin B. MooreWake Forest University
- Lee R. StonerUniversity of North Carolina at Chapel Hill
- Rui Li · correspondingWuhan University
Abstract
Type II diabetes mellitus (T2DM) is a metabolic disorder that occurs in the body because of decreased insulin activity and/or insulin secretion. The incidence of T2DM has rapidly increased over recent decades. The relation between consumption of different types of red meats and risk of T2DM remains uncertain. This meta-analysis was conducted to quantitatively assess the associations of processed red meat (PRM) and unprocessed red meat (URM) consumption with T2DM. We searched PubMed, Embase, Web of Science and The Cochrane Library for English-language cohort studies published before January 2021. Summary relative risks (RR) with 95% confidence interval (CI) were estimated using fixed effects and random effects. Additionally, dose-response relationships were explored using meta-regression. Fifteen studies (n = 682,963 participants, cases = 50,675) were identified. Compared with the lowest intake group, high consumption of PRM and URM increased T2DM risk by 27% (95% CI 1.15-1.40) and 15% (95% CI 1.08-1.23), respectively. These relationships were consistently strongest for U.S-based studies, though the effects of sex are inconclusive. In conclusion, PRM and URM are both positively associated with T2DM incidence, and these relationships are strongest in the U.S. reduction of red meat consumption should be explored as a target for T2DM prevention initiatives.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.