Systematic review2021Open access

Intake of Unprocessed and Processed Meat and the Association with Cardiovascular Disease: An Overview of Systematic Reviews

Jakobsen MU, Bysted A, Mejborn H, Stockmarr A, Trolle E

Nutrients · 18 citations

How it was studied

Design
Systematic review (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Not stated

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2021-09-22 · Nutrients · vol. 13 · issue 10 · p. 3303
Publisher
Multidisciplinary Digital Publishing Institute
Cited
25 citations · more than 70% of similar papers · 1.0× the field average
References
51 works
Access
Open access (journal) · CC-BY
Research areas
Nutritional Studies and Diet · Consumer Attitudes and Food Labeling · Agriculture Sustainability and Environmental Impact
Keywords
Meta-analysis, Medicine, Stroke (engine), Systematic review, Cohort study, Confidence interval, Red meat, Disease, Cohort, MEDLINE, Quality of evidence, Internal medicine, Pathology, Biology
MeSH
animals, poultry, humans, cardiovascular diseases, coronary disease, eating, meat, meta-analysis as topic, stroke, systematic reviews as topic

5 authors

From DK

  • Marianne Uhre Jakobsen · correspondingTechnical University of Denmark
  • Anette BystedTechnical University of Denmark
  • Heddie MejbornTechnical University of Denmark
  • Anders StockmarrTechnical University of Denmark
  • Ellen TrolleTechnical University of Denmark

Abstract

We conducted an overview of systematic reviews to summarize reviews of cohort studies on intake of unprocessed and processed meat and the risk of cardiovascular disease (CVD), coronary heart disease (CHD), and stroke. Systematic reviews of cohort studies published between January 2010 and August 2020 were identified through a systematic literature search in PubMed, Embase, and Web of Science. The quality of how each review was conducted was assessed and the overall confidence in the results of each review was rated using AMSTAR 2. The quality of evidence of each meta-analysis was graded using NutriGrade. Three reviews were included, with meta-analyses of unprocessed red meat and CVD (n = 1) and stroke (n = 2); unprocessed poultry and stroke (n = 1); and processed meat and CVD (n = 1), CHD (n = 1), and stroke (n = 3). The overall confidence in the results of each review was rated as critically low. The meta-evidence was graded moderate for a positive association between unprocessed red meat and stroke and moderate for a positive association between processed meat and CHD and stroke. For other associations the meta-evidence was graded as low or very low. In conclusion, the associations between unprocessed and processed meat with CVD and major subtypes of CVD have not been extensively investigated.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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