Egg Consumption and Blood Lipid Parameters According to the Presence of Chronic Metabolic Disorders: The EVIDENT II Study
Mesas AE, Garrido-Miguel M, Fernández-Rodríguez R, Fernández-Rodríguez R, Fernández Franco S, Lugones-Sánchez C, García-Ortiz L, Martínez-Vizcaíno V
The Journal of clinical endocrinology and metabolism · 6 citations
How it was studied
- Design
- Randomized controlled trial (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- European Commission
- Government
- Ministerio de Ciencia e Innovación
- Government
- Instituto de Salud Carlos III
- Government
- Spanish Ministry of Science and Innovation
- Government
- European Union
Based on 5 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2021-11-03 · J Clin Endocrinol Metab · vol. 107 · issue 3 · pp. e963–e972
- Publisher
- Oxford University Press
- Cited
- 7 citations · more than 76% of similar papers · 0.9× the field average
- References
- 44 works
- Access
- Open access (hybrid journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Food composition and properties · Consumer Attitudes and Food Labeling
- Keywords
- Dyslipidemia, Internal medicine, Quartile, Triglyceride, Endocrinology, Medicine, Cholesterol, Lipid profile, Blood lipids, Obesity, Metabolic syndrome, Diabetes mellitus, Physiology, Confidence interval
- MeSH
- humans, hypertension, diabetes mellitus, type 2, obesity, cross-sectional studies, feeding behavior, patient compliance, diet, mediterranean, eggs, adult, aged, middle aged, female, male, dyslipidemias, cholesterol, ldl, cholesterol, hdl, hypolipidemic agents
7 authors
From BR, ES, CL
- Arthur Eumann MesasUniversidade Estadual de Londrina; University of Castilla-La Mancha
- Miriam Garrido‐MiguelUniversity of Castilla-La Mancha
- Rubén Fernández-RodríguezUniversity of Castilla-La Mancha
- Sofía Fernández Franco
- Cristina Lugones‐SánchezInstituto de Investigación Biomédica de Salamanca; Gerencia Regional de Salud de Castilla y León (Sacyl)
- Luis García‐OrtizUniversidad de Salamanca; Red de Investigación en Actividades Preventivas y Promoción de la Salud; Instituto de Investigación Biomédica de Salamanca; Gerencia Regional de Salud de Castilla y León (Sacyl)
Abstract
Context
Egg consumption is one of the main dietary sources of cholesterol, but whether individuals who eat more eggs have a worse blood lipid profile remains controversial.
Objective
We examined the relationship between egg consumption and lipid parameters and explored whether this relationship changes according to the presence of chronic metabolic disorders.
Methods
A multicenter cross-sectional study was conducted with adult participants in the EVIDENT II trial. Adjusted linear regression models were stratified by the main chronic metabolic disorders.
Results
Among the 728 participants (61.9% women, mean age 52.1 ± 11.9 years), the mean egg consumption was equivalent to 5 to 6 eggs per week for a 70-kg individual. In the fully adjusted analysis, no association was found of egg consumption with total and high-density lipoprotein cholesterol (HDL-c), and triglyceride levels. Furthermore, compared with the first quartile of consumption, the fourth quartile was associated with lower low-density lipoprotein cholesterol (LDL-c) levels (coefficient -7.01; 95% CI -13.39, -0.62) and a lower LDL-c/HDL-c ratio (coefficient -0.24, 95% CI -0.41, -0.06). In the analyses stratified by chronic metabolic diseases, higher egg consumption was not associated with lipid profile in those with obesity, hypertension, type 2 diabetes, dyslipidemia, or treated with hypolipidemic drugs, and was associated with a better lipid profile in participants without these conditions.
Conclusion
Higher egg consumption was not associated with blood lipids in individuals with chronic metabolic disorders. In individuals without such conditions, the lipid profile was better among those who consumed more eggs. Our findings support current guidelines recommending eggs as part of a healthy diet.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.