Heat therapy shows benefit in patients with type 2 diabetes mellitus: a systematic review and meta-analysis
Sebők J, Édel Z, Váncsa S, Farkas N, Kiss S, Erőss B, Török Z, Balogh G, Balogi Z, Nagy R, Hooper PL, Geiger PC, Wittmann I, Vigh L, Dembrovszky F, Hegyi P
International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group · 21 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- European Regional Development Fund
Based on 1 listed funder(s).
Publication
- Published
- 2021-01-01 · Int J Hyperthermia · vol. 38 · issue 1 · pp. 1650–1659
- Publisher
- Taylor & Francis
- Cited
- 25 citations · more than 60% of similar papers · 0.6× the field average
- References
- 57 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Thermoregulation and physiological responses · Infrared Thermography in Medicine · Thermoelastic and Magnetoelastic Phenomena
- Keywords
- Medicine, Glycemic, Glycated hemoglobin, Meta-analysis, Internal medicine, Type 2 Diabetes Mellitus, Diabetes mellitus, Triglyceride, Randomized controlled trial, Confidence interval, Type 2 diabetes, MEDLINE, Endocrinology, Cholesterol
- MeSH
- humans, diabetes mellitus, type 2, blood glucose, hyperthermia, induced, hot temperature, glycated hemoglobin
16 authors
From HU, CN, US
- Judit SebőkUniversity of Pecs
- Zsófia ÉdelUniversity of Pecs
- Szilárd VáncsaSemmelweis University; University of Pecs
- Nelli FarkasUniversity of Pecs
- Szabolcs KissUniversity of Szeged
- Bálint Mihály ErőssSemmelweis University; University of Pecs
Abstract
Aims
Type-2 diabetes mellitus (T2DM) is a common health condition which prevalence increases with age. Besides lifestyle modifications, passive heating could be a promising intervention to improve glycemic control. This study aimed to assess the efficacy of passive heat therapy on glycemic and cardiovascular parameters, and body weight among patients with T2DM.
Methods
A systematic review and meta-analysis were reported according to PRISMA Statement. We conducted a systematic search in three databases (MEDLINE, Embase, CENTRAL) from inception to 19 August 2021. We included interventional studies reporting on T2DM patients treated with heat therapy. The main outcomes were the changes in pre-and post-treatment cardiometabolic parameters (fasting plasma glucose, glycated plasma hemoglobin, and triglyceride). For these continuous variables, weighted mean differences (WMD) with 95% confidence intervals (CIs) were calculated. Study protocol number: CRD42020221500.
Results
Five studies were included in the qualitative and quantitative synthesis, respectively. The results showed a not significant difference in the hemoglobin A1c [WMD -0.549%, 95% CI (-1.262, 0.164), p = 0.131], fasting glucose [WMD -0.290 mmol/l, 95% CI (-0.903, 0.324), p = 0.355]. Triglyceride [WMD 0.035 mmol/l, 95% CI (-0.130, 0.200), p = 0.677] levels were comparable regarding the pre-, and post intervention values.
Conclusion
Passive heating can be beneficial for patients with T2DM since the slight improvement in certain cardiometabolic parameters support that. However, further randomized controlled trials with longer intervention and follow-up periods are needed to confirm the beneficial effect of passive heat therapy.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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