The Effects of Fish Oil on Cardiovascular Diseases: Systematical Evaluation and Recent Advance
Liao J, Xiong Q, Yin Y, Ling Z, Chen S
Frontiers in cardiovascular medicine · 51 citations
How it was studied
- Design
- Systematic review (classified by our AI screen)
- Studied in
- People, plus animal or lab work
- Main outcome
- Clinical events such as disease or death
Who paid for it
- Funding
- Independent funding
- Government
- Chongqing Municipal Health Commission
- University or hospital
- Chongqing Medical University
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-01-05 · Front Cardiovasc Med · vol. 8 · p. 802306
- Publisher
- Frontiers Media
- Cited
- 87 citations · more than 99% of similar papers · 7.9× the field average
- Impact
- Top 10% most cited in its field
- References
- 136 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Fatty Acid Research and Health · Eicosanoids and Hypertension Pharmacology · Cholesterol and Lipid Metabolism
- Keywords
- Eicosapentaenoic acid, Docosahexaenoic acid, Fish oil, Medicine, Inflammation, Disease, Heart failure, Cardiology, Internal medicine, Coronary heart disease, Fatty acid, Pharmacology, Fish <Actinopterygii>, Polyunsaturated fatty acid, Biology, Biochemistry, Fishery
5 authors
From CN, DE
- Jia LiaoDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Qingsong XiongDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Yuehui YinDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Zhiyu Ling · correspondingDalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Chongqing Medical University
- Shaojie Chen · correspondingGoethe University Frankfurt; Dalian Medical University; Second Affiliated Hospital of Chongqing Medical University; Agaplesion Bethanien Krankenhaus; Agaplesion Markus Hospital; Chongqing Medical University
Abstract
Fish oil is rich in unsaturated fatty acids, i.e., eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), both of which are widely distributed in the body such as heart and brain. In vivo and in vitro experiments showed that unsaturated fatty acids may have effects of anti-inflammation, anti-oxidation, protecting vascular endothelial cells, thrombosis inhibition, modifying autonomic nerve function, improving left ventricular remodeling, and regulating blood lipid. Given the relevance to public health, there has been increasing interest in the research of potential cardioprotective effects of fish oil. Accumulated evidence showed that fish oil supplementation may reduce the risk of cardiovascular events, and, in specific, it may have potential benefits in improving the prognosis of patients with hypertension, coronary heart disease, cardiac arrhythmias, or heart failure; however, some studies yielded inconsistent results. In this article, we performed an updated systematical review in order to provide a contemporary understanding with regard to the effects of fish oil on cardiovascular diseases.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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