Meta-analysis2022

Beneficial effects of blueberry supplementation on the components of metabolic syndrome: a systematic review and meta-analysis

Azari H, Morovati A, Pourghassem Gargari B, Sarbakhsh P

Food & function · 8 citations

How it was studied

Design
Meta-analysis (indexed by PubMed)
Studied in
People
Main outcome
Health markers and function
Intake measured by
Not stated

Who paid for it

Funding
Independent funding
University or hospital
Tabriz University of Medical Sciences
Grants
Tabriz University of Medical Sciences (1400.02.26); Tabriz University of Medical Sciences (Pazhoohan 67677)

Based on 1 listed funder(s).

Publication

Published
2022-01-01 · Food Funct · vol. 13 · issue 9 · pp. 4875–4900
Publisher
Royal Society of Chemistry
Cited
13 citations · more than 52% of similar papers · 0.5× the field average
References
110 works
Access
Paywalled
Research areas
Natural Antidiabetic Agents Studies · Phytochemicals and Antioxidant Activities · Diet, Metabolism, and Disease
Keywords
Meta-analysis, Metabolic syndrome, Glycated hemoglobin, Medicine, Insulin resistance, Waist, Internal medicine, Body mass index, Homeostatic model assessment, Blood pressure, Endocrinology, Obesity, Diabetes mellitus, Type 2 diabetes
MeSH
humans, insulin resistance, blood glucose, triglycerides, body mass index, dietary supplements, blueberry plants, metabolic syndrome

4 authors

From IR

  • Hushyar AzariUrmia University; Urmia University of Medical Sciences
  • Ashti MorovatiTabriz University of Medical Sciences
  • Bahram Pourghassem Gargari · correspondingTabriz University of Medical Sciences
  • Parvin SarbakhshTabriz University of Medical Sciences

Abstract

Metabolic syndrome (MetS) is a combination of interconnected disorders that puts a heavy burden on society. This study investigated the impact of blueberry (BB) supplementation on components of MetS. A systematic search for studies in Embase, Science Direct, Cochrane and PubMed was done. Interventions for at least 2 weeks and studies which investigated the effects of BB on components of MetS in human subjects were included. 25 studies were eligible for inclusion in the review. 21 studies were included in the meta-analysis and the remaining 4 studies in the systematic review. The time range of the assessed studies was from 2007 to 2021. The results of the meta-analysis demonstrated that BB had no significant effect on waist circumference, body mass index (BMI), glycated hemoglobin (HbA1C), glucose level and homeostatic model assessment for insulin resistance (HOMA-IR); however, studies showed a significant improvement in systolic and diastolic blood pressure, triglycerides, total cholesterol, low-density lipoproteins (LDL), high-density lipoproteins (HDL) and insulin levels. In conclusion, the data in this meta-analysis show that BB supplementation is a beneficial option for the management of MetS in humans.

Abstract via Europe PMC. Copyright remains with the authors or publisher.

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