Intermittent Fasting versus Continuous Calorie Restriction: Which Is Better for Weight Loss?
Zhang Q, Zhang C, Wang H, Ma Z, Liu D, Guan X, Liu Y, Fu Y, Cui M, Dong J
Nutrients · 35 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Government
- Natural Science Foundation of Shandong Province
- Grants
- National Natural Science Foundation of China (No.31872791); Natural Science Foundation of Shandong Province (No. ZR2019MC046)
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-04-24 · Nutrients · vol. 14 · issue 9 · p. 1781
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 50 citations · more than 97% of similar papers · 4.8× the field average
- Impact
- Top 10% most cited in its field
- References
- 60 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Dietary Effects on Health · Diet and metabolism studies · Circadian rhythm and melatonin
- Keywords
- Medicine, Weight loss, Overweight, Cochrane Library, Meta-analysis, Body mass index, Calorie restriction, Randomized controlled trial, Confidence interval, Internal medicine, Strictly standardized mean difference, Publication bias, Obesity
- MeSH
- humans, body weight, weight loss, caloric restriction, fasting, overweight
10 authors
From CN
- Qing ZhangQingdao University
- Caishun ZhangQingdao University
- Haidan WangQingdao University
- Zhengye MaQingdao University
- Defeng LiuQingdao University
- Xiaohan GuanQingdao University
Abstract
We conducted a systematic review and meta-analysis of randomized clinical trials and pilot trial studies to compare the effectiveness of intermittent fasting (IF) and continuous calorie restriction (CCR) in overweight and obese people. The parameters included body mass index (BMI), body weight, and other metabolism-related indicators. A systematic search in PubMed, Embase, Cochrane Library, and Web of Science was conducted up to January 2022. Standardized mean differences (SMDs) with 95% confidence intervals (CIs) were used to measure the effectiveness. Publication bias was assessed using Egger's test. The stability of the results was evaluated using sensitivity analyses. The significance of body weight change (SMD = -0.21, 95% CI (-0.40, -0.02) p = 0.028) was more significant after IF than CCR. There was no significant difference in BMI (SMD = 0.02, 95% CI (-0.16, 0.20) p = 0.848) between IF and CCR. These findings suggest that IF may be superior to CCR for weight loss in some respects.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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