Cardiometabolic effects of early <i>v</i>. delayed time-restricted eating plus energetic restriction in adults with overweight and obesity: an exploratory randomised clinical trial
Queiroz JDN, Macedo RCO, Dos Santos GC, Munhoz SV, Machado CLF, de Menezes RL, Menzem EN, Moritz CEJ, Pinto RS, Tinsley GM, de Oliveira AR
The British journal of nutrition · 31 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Funding not disclosed
Publication
- Published
- 2022-05-26 · Br J Nutr · vol. 129 · issue 4 · pp. 637–649
- Publisher
- Cambridge University Press
- Cited
- 39 citations · more than 95% of similar papers · 3.6× the field average
- Impact
- Top 10% most cited in its field
- References
- 59 works
- Access
- Paywalled
- Research areas
- Dietary Effects on Health · Circadian rhythm and melatonin · Diet and metabolism studies
- Keywords
- Overweight, Medicine, Obesity, Weight loss, Internal medicine, Randomized controlled trial, Body mass index, Animal science, Biology
11 authors
From BR, US
- Jéssica do Nascimento Queiroz · correspondingUniversidade Federal do Rio Grande do Sul
- Rodrigo Cauduro Oliveira MacedoUniversidade Federal do Rio Grande do Sul; Universidade de Santa Cruz do Sul
- Gabriela Cristina dos SantosUniversidade Federal do Rio Grande do Sul
- Samuel Vargas MunhozUniversidade Federal do Rio Grande do Sul
- Carlos Leonardo Figueiredo MachadoUniversidade Federal do Rio Grande do Sul
- Rodrigo Leal-MenezesUniversidade Federal do Rio Grande do Sul
Abstract
This exploratory study investigated the effects of early v. delayed time-restricted eating (TRE) plus caloric restriction (CR) on body weight, body composition and cardiometabolic parameters in adults with overweight and obesity. Adults (20-40 years) were randomised to one of three groups for 8 weeks: early time-restricted eating (eTRE; 08.00-16.00) plus CR, delayed time-restricted eating (dTRE; 12.00-20.00) plus CR or only CR (CR; 08.00-20.00). All groups were prescribed a 25 % energy deficit relative to daily energy requirements. Thirteen participants completed the study in the eTRE and CR groups and eleven in the dTRE group (n 37). After the interventions, there was no significant difference between the three groups for any of the outcomes. Compared with baseline, significant decreases were observed in the body weight (eTRE group: -4·2 kg; 95 % CI, -5·6, -2·7; dTRE group: -4·8 kg; 95 % CI, -5·9, -3·7; CR: -4·0 kg; 95 % CI, -5·9, -2·1), fat mass (eTRE group: -2·9 kg; 95 % CI, -3·9, -1·9; dTRE group: -3·6 kg; 95 % CI, -4·6, -2·5; CR: -3·1 kg; 95 % CI, -4·3, -1·8) and fasting glucose levels (eTRE group: -4 mg/dl; 95 % CI, -8, -1; dTRE group: -2 mg/dl; 95 % CI, -8, 3; CR: -3 mg/dl; 95 % CI, -8, 2). In a free-living setting, TRE with a energetic deficit, regardless of the time of day, promotes similar benefits in weight loss, body composition and cardiometabolic parameters. However, given the exploratory nature of our study, further investigation is needed to confirm these findings.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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