Ultra-processed Foods Consumption Increases the Risk of Hypertension in Adults: A Systematic Review and Meta-analysis
Wang M, Du X, Huang W, Xu Y
American journal of hypertension · 60 citations
How it was studied
- Design
- Meta-analysis (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- University or hospital
- Southwest Medical University
- Government
- Sichuan Science and Technology Program
- University or hospital
- Luzhou-Southwest Medical University cooperation project, Luzhou, Sichuan, China
- Grants
- Southwest Medical University (2018LZXNYD-PT01); Southwest Medical University (2020YFS0456); Southwest Medical University (2019YFS0537)
Based on 3 listed funder(s).
Publication
- Published
- 2022-06-24 · Am J Hypertens · vol. 35 · issue 10 · pp. 892–901
- Publisher
- Oxford University Press
- Cited
- 78 citations · more than 96% of similar papers · 4.0× the field average
- Impact
- Top 10% most cited in its field
- References
- 59 works
- Access
- Free to read
- Research areas
- Consumer Attitudes and Food Labeling · Nutritional Studies and Diet · Nutrition, Genetics, and Disease
- Keywords
- Medicine, Meta-analysis, Odds ratio, Confidence interval, Observational study, Cochrane Library, Body mass index, Incidence (geometry), Environmental health, Population, Internal medicine
- MeSH
- humans, hypertension, body mass index, diet, incidence, energy intake, adult
4 authors
From CN
- Mei WangAffiliated Hospital of Southwest Medical University; First Affiliated Hospital of Sichuan Medical University; Shanghai Clinical Research Center
- Xinyi DuAffiliated Hospital of Southwest Medical University; First Affiliated Hospital of Sichuan Medical University; Shanghai Clinical Research Center
- Wei HuangAffiliated Hospital of Southwest Medical University; First Affiliated Hospital of Sichuan Medical University; Shanghai Clinical Research Center
- Yong Xu · correspondingAffiliated Hospital of Southwest Medical University; First Affiliated Hospital of Sichuan Medical University; Shanghai Clinical Research Center
Abstract
Background
Effect of ultra-processed foods (UPFs) consumption on health has attracted widespread attention in recent years. However, the relationship between UPFs consumption and hypertension is unclear. This meta-analysis was conducted to analyze the above association.
Methods
We systematically searched PubMed, Embase, and Cochrane Library for all relevant studies published up to 31 January 2022 without language limitation. The random-effects model was selected to pool the effect sizes and 95% confidence intervals (CIs).
Results
Nine observational studies involving 111,594 participants were included. Results from this meta-analysis showed that higher UPFs consumption significantly increased the risk of hypertension (odds ratio: 1.23; 95% CI: 1.11, 1.37; P = 0.034). Furthermore, analyses were performed based on gender, study design, exposure assessment, outcome assessment, body mass index, energy intake, and physical activity, which suggested that the results remained statistically significant.
Conclusions
Our findings suggested that UPFs might have detrimental effects on the incidence of hypertension in the general population. Although current evidence is limited, it cannot be denied that reducing consumption of UPFs may contribute to decrease the risk of chronic noncommunicable diseases.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
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