Study2022Open access

Comparative effects of music interventions on depression in older adults: A systematic review and network meta-analysis

Dhippayom T, Saensook T, Promkhatja N, Teaktong T, Chaiyakunapruk N, Devine B

EClinicalMedicine · 29 citations

How it was studied

Design
Meta-analysis (classified by our AI screen)
Studied in
People
Main outcome
Health markers and function

Who paid for it

Funding
Independent funding

Based on full-text disclosure statement.

Publication

Published
2022-07-01 · EClinicalMedicine · vol. 50 · p. 101509
Publisher
Elsevier BV
Cited
42 citations · more than 80% of similar papers · 1.6× the field average
References
55 works
Access
Open access (journal) · CC-BY-NC-ND
Research areas
Music Therapy and Health · Health and Well-being Studies · Art Therapy and Mental Health
Keywords
Medicine, Music therapy, Psychological intervention, Randomized controlled trial, Meta-analysis, Confidence interval, MEDLINE, Depression (economics), CINAHL, Intervention (counseling), Physical therapy, Psychiatry, Internal medicine

6 authors

From TH, US

  • Teerapon Dhippayom · correspondingNaresuan University
  • Thitinan SaensookNaresuan University
  • Natthamon PromkhatjaNaresuan University
  • Thanasak TeaktongNaresuan University
  • Nathorn ChaiyakunaprukUniversity of Utah; VA Salt Lake City Healthcare System
  • Beth DevineUniversity of Washington

Abstract

Background

The effect of different music interventions on depression in older adults is varied. We aimed to explore the comparative effect of different music intervention features on depression in older adults.

Methods

We searched PubMed, EMBASE, CENTRAL, CINAHL, and ProQuest Dissertations&Theses from inception to October 2021 for randomized controlled trials (RCTs) of music interventions in participants aged ≥60 years. Music interventions were classified based on the TIP (theme, intensity, and provider/platform) framework. The theme was divided into: 1) active music therapy (ACT); 2) receptive music therapy (Recep); and 3) music medicine (MM). The intensity was classified as high (>60 minutes/week), and low (≤60 minutes/week). The provider was classified as a music therapist (MT) or a non-music therapist (NonMT). Summary standardized mean differences (SMD) of level of depression with 95% confidence interval (CI) were estimated using a frequentist framework with a random-effects model. The certainty of evidence was evaluated using the Confidence in Network Meta-Analysis (CINeMA) approach. This study was registered with PROSPERO (CRD42021247165).

Findings

Fifteen RCTs involving 1,144 older adults (mean age 67.9-86.6 years) were included. When compared with usual care, the most effective music intervention was active music therapy >60 minutes/week by music therapist (Act/High/MT) (SMD -3.00; 95%CI, -3.64,-2.35), followed by music medicine >60 minutes/week by non-music therapist (MM/High/NonMT) (SMD -2.06; 95%CI, -2.78,-1.35) with moderate and high certainty of evidence, respectively. Depression scores in older adults treated with ACT/High/MT was also significantly lower than all other interventions, except MM/High/NonMT. Low intensity music interventions other than Act/Low/MT had no impact on depression.

Interpretation

Although active music therapy >60 minutes/week by music therapist is the most effective intervention to alleviate depression in older adults, music medicine by listening to music of older adult's own preference >60 minutes/week is an alternative approach in settings with limited resources.

Funding

None.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC-ND).

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