The Effect of Whole-Grain Diet on the Gut Microbiota of the Elderly Individuals
Cui Z, Li J, Zhen Y, Fan P, Du G
Frontiers in nutrition · 5 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Mechanisms only
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Government
- Natural Science Foundation of Hainan Province
- Grants
- Natural Science Foundation of Hainan Province (821MS0830); National Natural Science Foundation of China (81960672)
Based on 2 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-06-27 · Front Nutr · vol. 9 · p. 919838
- Publisher
- Frontiers Media
- Cited
- 8 citations · more than 66% of similar papers · 0.7× the field average
- References
- 51 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Diet and metabolism studies · Gut microbiota and health · Nutrition, Health and Food Behavior
- Keywords
- Gut flora, Whole grains, Food science, Gut microbiome, Biology, Western diet, Medicine, Obesity, Immunology, Endocrinology
5 authors
From CN
- Zeying CuiHainan Medical University
- Jingtai LiHainan Medical University
- Yuting ZhenHainan Medical University
- Pingming Fan · correspondingHainan Medical University
- Guankui Du · correspondingHainan Medical University
Abstract
A whole-grain (WG) diet affects human health in multiple ways. However, the effect of WG on the gut microbiota of the elderly individuals is still largely unknown. In this study, WG did not affect the microbial α-diversity but had a profound impact on the microbes' abundance in the elderly individuals. WG increased the abundance of Verrucomicrobia and decreased the abundance of Firmicutes. The prediction of microbial function showed that glucose metabolism and lipid metabolism were inhibited. In addition, the effects of WG on the gut microbiota of normal-weight (NW) and overweight (OW) individuals were different. WG increased Verrucomicrobia in the NW group and decreased Firmicutes in the OW group. Meanwhile, the effect of WG on gut microbiota showed gender characteristics, Firmicutes/Bacteroidetes ratio was decreased in women, while Verrucomicrobia abundance was increased in men. The use of WG could improve the microbial composition and promote the growth of beneficial microbes, which may be beneficial to the health of the elderly individuals.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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