Effect of standardized root extract of ashwagandha (Withania somnifera) on well-being and sexual performance in adult males: A randomized controlled trial
Chauhan S, Srivastava MK, Pathak AK
Health science reports · 33 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Randomized controlled trial (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Possibly industry funded
- Authors
- At least one author declares a financial tie to industry
Based on full-text disclosure statement.
Publication
- Published
- 2022-07-01 · Health Sci Rep · vol. 5 · issue 4 · p. e741
- Publisher
- Wiley
- Cited
- 45 citations · more than 98% of similar papers · 9.4× the field average
- Impact
- Top 10% most cited in its field
- References
- 40 works
- Access
- Open access (journal) · CC-BY-NC
- Research areas
- Phytochemicals and Medicinal Plants · Sexual function and dysfunction studies · Pharmacology and Nanomedicine Research
- Keywords
- Withania somnifera, Aphrodisiac, Placebo, Medicine, Testosterone (patch), Randomized controlled trial, Traditional medicine, Physiology, Internal medicine, Alternative medicine
3 authors
From IN
- Sanjaya Chauhan · correspondingNarayana Health
- Manoj Kumar Srivastava
- Anklesh Kumar PathakM.V. Hospital and Research Centre; Centre of Biomedical Research
Abstract
Background and aim
In Ayurveda, ashwagandha is a popular plant for promoting youthful energy, longevity, and overall well-being. It is also an excellent aphrodisiac herb that aids in the improvement and maintenance of normal sexual health. The present study aims to evaluate the effect of ashwagandha root extract on improving sexual health in adult males.
Methods
In this 8-week randomized, double-blind, placebo-controlled study, we investigated the aphrodisiac property of an ashwagandha root extract in adult males. Fifty participants with lower sexual desire were randomly allocated to take 300 mg of ashwagandha root extract or placebo capsules twice daily. Outcomes were measured using the derogatis interview for sexual functioning-male (DISF-M) questionnaire, serum testosterone, serum prolactin, and short-form survey-36 quality of life questionnaire before and after the intervention.
Results
Compared to placebo, ashwagandha root extract supplementation was associated with a statistically significant increase in the total DISF-M scores (mean difference -9.8; 95% confidence interval, -10.73 to -8.87; p t-test). It was also associated with a statistically significant increase in serum testosterone levels (-66.52; -80.70 to -52.34; p t-test). However, the prolactin level did not change after intervention in both the ashwagandha and placebo groups (-1.06; -2.78 to 0.66; p > 0.05).
Conclusion
These findings suggest that ashwagandha demonstrated a significant subjective perception of sexual well-being and assisted in increasing serum testosterone levels in the participants.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY-NC).
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