Associations of ultra-processed food consumption with cardiovascular disease and all-cause mortality: UK Biobank
Chen X, Chu J, Hu W, Sun N, He Q, Liu S, Feng Z, Li T, Han Q, Shen Y
European journal of public health · 59 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Not stated
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Government
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Government
- Medical Research Council
- Grants
- Medical Research Council (MC_PC_17228); National Natural Science Foundation of China (81973143)
Based on 3 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-08-25 · Eur J Public Health · vol. 32 · issue 5 · pp. 779–785
- Publisher
- Oxford University Press
- Cited
- 69 citations · more than 99% of similar papers · 11.1× the field average
- Impact
- Top 10% most cited in its field
- References
- 41 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Consumer Attitudes and Food Labeling · Nutrition, Genetics, and Disease · Nutritional Studies and Diet
- Keywords
- Medicine, Hazard ratio, Confidence interval, Internal medicine, Incidence (geometry), Proportional hazards model, Cause of death, Cohort study, Disease
- MeSH
- humans, cardiovascular diseases, diet, risk factors, prospective studies, biological specimen banks, fast foods, united kingdom
10 authors
From CN
- Xuanli ChenSoochow University
- Jiadong ChuSoochow University
- Wei HuSoochow University
- Na SunSoochow University
- Qida HeSoochow University
- Siyuan LiuSoochow University
Abstract
Background
This study aimed to investigate the associations between ultra-processed food (UPF) consumption and the risk of cardiovascular disease and all-cause mortality in the UK Biobank Cohort.
Methods
This observational prospective study evaluated 60 298 participants aged 40 years or older. We used the NOVA classification system to identify and categorize UPF. The associations among UPF consumption, cardiovascular disease (CVD) incidence and all-cause mortality were estimated using multivariable Cox proportional hazards models. Dose-response analysis of UPF consumption and CVD incidence and mortality was performed using a restricted cubic spline.
Results
After a median follow-up of 10.9 years, 6048 participants (10.0%) experienced CVD events, and 5327 (8.8%) and 1503 (2.5%) experienced coronary heart and cerebrovascular diseases, respectively. There were 2590 (4.3%) deaths, of which 384 (0.6%) deaths were caused by CVD. A higher intake of UPF was associated with a higher risk of CVD and all-cause mortality (all P 0.30).
Conclusions
A higher proportion of UPF consumption was associated with CVD and all-cause mortality. Thus, actions to limit UPF consumption should be incorporated into the CVD and all-cause mortality prevention recommendations.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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