Relative to processed red meat, alternative protein sources are associated with a lower risk of hypertension and diabetes in a prospective cohort of French women
Thao U, Lajous M, Laouali N, Severi G, Boutron-Ruault MC, MacDonald CJ
The British journal of nutrition · 6 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- Government
- Agence Nationale de la Recherche
- Government
- Institut National de la Santé et de la Recherche Médicale
- Nonprofit
- Ligue Contre le Cancer
- University or hospital
- Institut Gustave-Roussy
- Nonprofit
- Mutuelle Générale de l'Education Nationale
- Grants
- Agence Nationale de la Recherche (ANR-10-COHO-0006); Institut National de la Santé et de la Recherche Médicale (ANR-10-COHO-0006); Mutuelle Générale de l'Education Nationale (ANR-10-COHO-0006); Agence Nationale de la Recherche (ANR-10)
Based on 5 listed funder(s).
Publication
- Published
- 2022-09-01 · Br J Nutr · vol. 129 · issue 11 · pp. 1964–1975
- Publisher
- Cambridge University Press
- Cited
- 7 citations · more than 75% of similar papers · 1.0× the field average
- References
- 0 works
- Access
- Open access (repository copy)
- Research areas
- Nutritional Studies and Diet · Meat and Animal Product Quality · Fatty Acid Research and Health
- Keywords
- Diabetes mellitus, Medicine, Red meat, Hazard ratio, Prospective cohort study, Relative risk, Lower risk, Internal medicine, Proportional hazards model, Cohort, Cohort study, Confidence interval, Environmental health, Endocrinology, Pathology
- MeSH
- animals, vegetables, hypertension, diabetes mellitus, diet, risk factors, cohort studies, prospective studies, meat, red meat
6 authors
From FR, EC, MX, US, IT, SE
- Uyen ThaoUniversité de Bordeaux; Inserm; Université de Versailles Saint-Quentin-en-Yvelines; Université de Lille; Centre Hospitalier Universitaire de Lille; Centre de recherche en Epidémiologie et Santé des Populations
- Martín LajousInstituto Nacional de Investigación en Salud Pública; Instituto Nacional de Salud Pública; Harvard Global Health Institute
- Nasser LaoualiInserm; Université de Versailles Saint-Quentin-en-Yvelines; Centre de recherche en Epidémiologie et Santé des Populations
- Gianluca SeveriInserm; Université de Versailles Saint-Quentin-en-Yvelines; Centre de recherche en Epidémiologie et Santé des Populations; University of Florence
- Marie‐Christine Boutron‐RuaultInserm; Université de Versailles Saint-Quentin-en-Yvelines; Centre de recherche en Epidémiologie et Santé des Populations
- Conor‐James MacDonald · correspondingInserm; Université de Versailles Saint-Quentin-en-Yvelines; Karolinska Institutet; Centre de recherche en Epidémiologie et Santé des Populations
Abstract
Many dietary guidelines recommend restricting the consumption of processed red meat (PRM) in favour of healthier foods such as fish, to reduce the risk of chronic conditions such as hypertension and diabetes. The objective of this study was to estimate the potential effect of replacing PRM for fatty fish, lean fish, red meat, eggs, pulses, or vegetables, on the risk of incident hypertension and diabetes. This was a prospective study of women in the E3N cohort study. Cases of diabetes and hypertension were based on self-report, specific questionnaires, and drug reimbursements. In the main analysis, information on regular dietary intake was assessed with a single food history questionaire, and food substitutions were modelled using cox proportional hazard models. 95 % confidence intervals were generated via bootstrapping. 71 081 women free of diabetes and 45 771 women free of hypertension were followed for an average of 18·7 and 18·3 years, respectively. 2681 incident cases of diabetes and 12 327 incident cases of hypertension were identified. Relative to PRM, fatty fish was associated with a 15 % lower risk of diabetes (HR = 0·85, 95 CI (0·73, 0·97)) and hypertension (HR = 0 85 (0·79, 0·91)). Between 3 and 10 % lower risk of hypertension or diabetes was also observed when comparing PRM with vegetables, unprocessed red meat or pulses. Relative to PRM, alternative protein sources such as fatty fish, unprocessed red meat, vegetables or pulses was associated with a lower risk of hypertension and diabetes.
Abstract via Europe PMC. Copyright remains with the authors or publisher.
Community trust
Loading…
How much do you trust this study's findings?
Comments
Sign in to rate, comment on or flag this study.Sign inSomething wrong here?
Flag this study if its information, labels or funding look wrong. An editor reviews every flag.
Sign in to rate, comment on or flag this study.Sign inEducational information about published research. Not medical advice, and not a recommendation to start or stop anything.