Associations between dietary magnesium intake and handgrip strength were modified by serum vitamin D level among the US elderly
Han S, Gao Y, Gan D
Frontiers in nutrition · 2 citations
How it was studied
- Design
- Cross-sectional study (classified by our AI screen)
- Studied in
- People
- Main outcome
- Health markers and function
Who paid for it
- Funding
- Independent funding
- Government
- National Natural Science Foundation of China
- Government
- China Postdoctoral Science Foundation
- Government
- Centers for Disease Control and Prevention
- Government
- Natural Science Foundation of Zhejiang Province
- Grants
- National Natural Science Foundation of China (82100904); Natural Science Foundation of Zhejiang Province (LQ21C110001)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-10-12 · Front Nutr · vol. 9 · p. 1002634
- Publisher
- Frontiers Media
- Cited
- 3 citations · more than 52% of similar papers · 0.3× the field average
- References
- 44 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Magnesium in Health and Disease · Vitamin D Research Studies · Parathyroid Disorders and Treatments
- Keywords
- Magnesium, Medicine, National Health and Nutrition Examination Survey, Dietary Reference Intake, Vitamin D and neurology, Hand strength, Internal medicine, Endocrinology, Muscle strength, Animal science, Nutrient, Grip strength, Physical therapy, Chemistry, Population, Environmental health, Biology
3 authors
From CN
- Shuang HanAffiliated Hangzhou First People's Hospital, Westlake University, School of Medicine; Zhejiang University
- Yue Gao · correspondingAffiliated Hangzhou First People's Hospital, Westlake University, School of Medicine; Zhejiang University
- Da Gan · correspondingChildren's Hospital of Zhejiang University; Zhejiang University
Abstract
Objective
The present study aimed to evaluate the associations between dietary magnesium intake and handgrip strength, and whether these associations were affected by serum vitamin D status.
Methods
A total of 2,127 participants aged 60 and above from the National Health and Nutrition Examination Survey (NHANES) of the 2011-2014 cycles were included in the analyses. Magnesium intake was obtained by 24-h dietary recalls and 30-day dietary supplement. Participants in the lowest sex-specific tertile of magnesium intake were defined as having low magnesium intake. Serum 25-hydroxyvitamin D [25(OH)D)] concentrations were examined by using ultra-high performance liquid chromatography tandem mass spectrometry and categorized into three levels: deficient, suboptimal, and sufficient. Handgrip strength was determined by using a dynamometer. Multivariable linear regression models were used to investigate the associations between dietary magnesium intake and handgrip strength.
Results
Low magnesium intake was not associated with handgrip strength, but interactions between low magnesium intake and serum 25(OH)D level existed on handgrip strength. The stratified analyses found that only in participants with deficient serum 25(OH)D, low magnesium intake was associated with reduced handgrip strength. The combined analyses shown that participants with both low magnesium intake and deficient serum 25(OH)D had highest decrease of handgrip strength.
Conclusion
Findings suggested that low magnesium intake was associated with reduced handgrip strength only in participants with deficient serum 25(OH)D. Increased magnesium intake was recommended for participants with deficient serum 25(OH)D in maintaining muscle strength.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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