Systematic review2022Open access

Olive oil consumption and risk of cardiovascular disease and all-cause mortality: A meta-analysis of prospective cohort studies

Xia M, Zhong Y, Peng Y, Qian C

Frontiers in nutrition · 37 citations

How it was studied

Design
Systematic review (indexed by PubMed)
Studied in
People
Main outcome
Clinical events such as disease or death
Intake measured by
Not stated

Who paid for it

Funding
Independent funding
University or hospital
Southwest Medical University

Based on 1 listed funder(s) and full-text disclosure statement.

Publication

Published
2022-10-18 · Front Nutr · vol. 9 · p. 1041203
Publisher
Frontiers Media
Cited
54 citations · more than 62% of similar papers · 0.7× the field average
References
45 works
Access
Open access (journal) · CC-BY
Research areas
Edible Oils Quality and Analysis · Nutritional Studies and Diet · Fatty Acid Research and Health
Keywords
Medicine, Relative risk, Prospective cohort study, Meta-analysis, Confounding, Cohort study, Confidence interval, Lower risk, Internal medicine, Epidemiology

4 authors

From CN

  • Xia MengAffiliated Hospital of Southwest Medical University
  • Yi ZhongAffiliated Hospital of Southwest Medical University
  • Yongquan PengAffiliated Hospital of Southwest Medical University
  • Cheng Qian · correspondingAffiliated Hospital of Southwest Medical University

Abstract

Background

Epidemiological studies have shown the preventive effects of olive oil consumption against cardiovascular events and all-cause deaths, but the results remain inconsistent. Herein, we performed a meta-analysis to elucidate this association.

Materials and methods

A systematical literature search was conducted in online databases (PubMed and Scopus) through July 31, 2022. Prospective cohort studies providing the risk of total cardiovascular disease (CVD) or all-cause mortality for olive oil consumption were included. Relative risks (RRs) and 95% confidence intervals (CIs) were aggregated using random-effect model.

Results

This meta-analysis included 13 studies comprising a total of 13 prospective cohorts. Compared with lower consumption, higher consumption of olive oil conferred a significantly reduced risk in CVD (RR: 0.85, 95% CI: 0.77-0.93, p p p = 0.005) for CVD and 0.96 (95% CI: 0.95-0.96, p p for non-linearity < 0.001), with little additional or no risk reduction observed beyond the consumption of approximately 20 g/days.

Conclusion

Olive oil consumption is inversely related to the risk of CVD and all-cause mortality. Such benefits seem to be obtained with an intake of olive oil up to 20 g/days, which deserves further exploration in future studies.

Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).

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