Frequency of Egg Intake Associated with Mortality in Chinese Adults: An 8-Year Nationwide Cohort Study
Wang K, Xiang Q, Hu L, Wang L, Zhang Y
International journal of environmental research and public health · 6 citations
Review labels
Neutral facts our review recorded about how this study was done. They describe method, never whether we like the result.
How it was studied
- Design
- Cohort study (indexed by PubMed)
- Studied in
- People
- Main outcome
- Clinical events such as disease or death
- Intake measured by
- Food frequency questionnaire
Who paid for it
- Funding
- Independent funding
- University or hospital
- Peking University
- University or hospital
- Hubei University of Medicine
- University or hospital
- Hubei University
- University or hospital
- Key Research Center for Humanities and Social Sciences in Hubei Province (Hubei University of Medicine)
- Grants
- Hubei University of Medicine (2022ZD001)
Based on 4 listed funder(s) and full-text disclosure statement.
Publication
- Published
- 2022-11-10 · Int J Environ Res Public Health · vol. 19 · issue 22 · p. 14777
- Publisher
- Multidisciplinary Digital Publishing Institute
- Cited
- 7 citations · more than 78% of similar papers · 1.2× the field average
- References
- 50 works
- Access
- Open access (journal) · CC-BY
- Research areas
- Nutritional Studies and Diet · Obesity, Physical Activity, Diet · Consumer Attitudes and Food Labeling
- Keywords
- Demography, Hazard ratio, Medicine, Cohort, Proportional hazards model, Cohort study, Confidence interval, Lower risk, Environmental health, Internal medicine
- MeSH
- humans, cardiovascular diseases, proportional hazards models, cohort studies, adolescent, adult, aged, aged, 80 and over, middle aged, china, young adult, asian people
5 authors
From CN
- Ke WangWuhan University of Science and Technology
- Qianqian XiangHubei Provincial Center for Disease Control and Prevention
- Lan HuHubei Cancer Hospital; Wuhan University of Science and Technology; Huazhong University of Science and Technology
- Lu Wang · correspondingHubei University of Arts and Science
- Yunquan Zhang · correspondingWuhan University of Science and Technology
Abstract
Whether egg consumption plays a beneficial/detrimental role in affecting human health and longevity has been debated for decades. Large-scale cohort evidence from low- and middle-income populations are scarce. In this study, we aimed to assess the association of egg consumption with mortality in Chinese adults. A nationwide cohort of 30,835 participants ages 16-110 years were enrolled from 25 provincial regions in China's mainland. Dietary intake (e.g., egg, meat, vegetable) was assessed by a food-frequency questionnaire. Cox proportional hazards models were used to examine associations between egg consumption and mortality, adjusting for demographic characteristics, dietary factors and health status. Dose-response relationships were investigated using the smoothing function of restricted cubic splines. Several subgroup analyses were performed. A total of 1651 all-cause deaths occurred during a median follow-up of 8.1 years. Egg consumption was associated with lower risks of mortality, with the lowest risk occurring in the group of moderate egg intake (3-6 times/week). Compared with non-consumers, the hazard ratios (95% confidence intervals) for mortality were 0.84 (0.72-0.97) for 3-6 times/week and 0.82 (0.69-0.98) for ≥7 times/week, whereas no significant associations were observed among the lower egg intake group (1-2/week). An approximately inverted J-shaped association was observed in three models, while restricting our analysis in the multivariable model (model 3) did not identify a significant violation for the linear relationship (p for nonlinear = 0.122). There were no statistically significant effect modifications in the subgroup analyses. Egg consumption may be associated with lower risks of mortality in Chinese adults. Our findings found moderate-to-high egg consumption might be beneficial for improving long-term health and longevity.
Abstract via Europe PMC. Copyright remains with the authors or publisher (CC BY).
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